The genetic code is the blueprint of an organism written on a stable molecule class: deoxyribonucleic acid. With the method CRISPR/Cas9, editing the genetic information has become much easier. This technique is a blessing for basic scientists, as well as for translational researchers such as Dr. Kathleen Börner, who wants to develop a gene therapy for infections caused by human immunodeficiency virus (HIV)….

They are multipotent, interact closely with endothelial cells, and are involved in immunosurveillance: the heterogeneous group of pericytes. These cells build the wall of blood vessels, and play a crucial role in the formation and maintenance of the vasculature. Due to their involvement in various pathophysiologies such as tumor angiogenesis, scientists are beginning to exploit their potential for therapeutic approaches….

Skin is the primary focus of cosmetic research. Since the European Union banned animal testing of cosmetics completely in 2013, three-dimensional skin models have been used to evaluate epidermal and dermal responses to cosmetic formulations. Such models provide a reliable tool to assess the functionality and safety of new cosmetic products….

It adapts quickly to the cellular defense mechanisms of the host and develops resistance against antiviral drugs: The influenza A virus is a major human pathogen with high variability. New super-resolution microscopy methods, as well as the use of human primary cells, currently allow better insights into the interactions between viruses and host cells….