Disease Cell Models We offer a large selection of cell donors with known disease status suitable for drug discovery and research applications. Why do you need diseased cells? What do we offer? Available cell types The availability of human cells that play a key role in diseases is vital to understand the disease at a cellular level. Relevant models enable experiments under physiologic conditions and are key for developing new therapies for chronic diseases. A cell disease model is an in vitro culture of cells isolated from a tissue donor with a known disease condition. By studying cell disease models, researchers gain insights in how diseases develop, and this also enables them to look for new molecular targets for specific therapies. In addition, cell disease models can be used for testing potential treatment approaches. With our comprehensive portfolio of products and services for human cell culture, we support scientists worldwide in advancing research and developing safer drugs. Send us your request! Fill out our request form and let us know your donor requirements. Our team of scientific support specialists will contact you directly and help you find the best solution for your specific research needs. Our cells from diseased donors feature the same specifications and undergo the same rigid quality control tests as cells from healthy donors from our human primary cell portfolio (marker characterization, growth performance, morphology, etc.). Streamlined tissue procurement with established partners allows us to source tissues on regular basis and hence offer wide variety of cells from diseased donors with appropriate lot sizes that are consistent for your scientific studies. All cell types from diseased donors can be cultured using our matching growth media to ensure optimal growth performance for your experiments. Main advantages include: All cell types from diseased donors are cryopreserved at the end of the first passage after tissue isolation (with the exception of HCAEC, which are cryopreserved after the second passage) Verified cell identity by cell marker expression and morphology Tested cell growth performance and morphology during several passages for each lot Flexible cell lot/donor reservations Send us your request! Fill out our request form and let us know your donor requirements. Our team of scientific support specialists will contact you directly and help you find the best solution for your specific research needs. Diabetes Type I and II Cardiac Myocytes (HCM) Preadipocytes (subcutaneous HWP) Aortic Smooth Muscle Cells (HAoSMC) Aortic Endothelial Cells (HAoEC) Coronary Artery Smooth Muscle Cells (HCASMC) Coronary Artery Endothelial Cells (HCAEC) Dermal Keratinocytes (NHEK adult) Respiratory Diseases (COPD Type I – IV, Asthma) Bronchial Epithelial Cell (HBEpC) Small Airway Epithelial Cells (HSAEpC) Bronchial Smooth Muscle Cells (HBSMC) Pulmonary Fibroblasts (HPF) Send us your request! Fill out our request form and let us know your donor requirements. Our team of scientific support specialists will contact you directly and help you find the best solution for your specific research needs.