Human Dermal Lymphatic Endothelial Cells (HDLEC)

Primary Human Dermal Lymphatic Endothelial Cells isolated from different sources (e.g. juvenile foreskin). CD31 positive, Podoplanin positive.

Choose Variant
×

Selected product Human Dermal Lymphatic Endothelial Cells (HDLEC)

juvenile foreskin, cryopreserved 500,000 cells

adult, cryopreserved 500,000 cells

juvenile foreskin, proliferating 500,000 cells

adult, proliferating 500,000 cells

juvenile foreskin, cell pellet in RNAlater 1,000,000 cells

adult, cell pellet in RNAlater 1,000,000 cells

Add to cart to purchase or to request a quote

This product is not currently available.

Primary Human Dermal Lymphatic Endothelial Cells (HDLEC) are a subpopulation of the Human Dermal Endothelial Cells. They are isolated from the dermis of juvenile foreskin and adult skin (different locations) from a single donor. The cells are analyzed positive for CD31 and podoplanin by flow cytometric analysis.
(Human Dermal Blood Endothelial Cells (HDBEC) from the same donor are available on request.)

Lymphatic vessels transport excess fluids from tissues to the circulatory system and are a major component of the immune system. The transported fluid is nearly cell free. The vessels are highly permeable, because they lack a continuous basal membrane. Lymphatic endothelial cells are involved in pathological alterations of the lymphatic system. During tumor lymphangiogenesis, the lymphatic endothelial cells build new vessels that infiltrate tumors, attract tumor cells, and induce tumor cell metastasis.

NEW: Our HDLEC are now also available from HLA-typed donors.

Available formats:

  • Cryopreserved: Cryogenic vial containing 500.000 viable cells.
  • Proliferating: >500.000 viable cells shipped in growth medium (T25 flask).
  • Cell pellet: 1 million cells dissolved in 200µl RNAlater© for subsequent RNA, DNA or protein analysis. Cell pellets cannot be revived.
Recommended plating density 10,000 – 20,000 cells per cm2
Passage After Thawing P2
Tested Markers Podoplanin positive, CD31 positive
Guaranteed Population Doubling > 15
Human Dermal Lymphatic Endothelial Cell Culture
Figure 1.
Human Dermal Lymphatic Endothelial Cell Culture
Figure 1.
human-dermal-lymphatic-endothelial-cell-culture-flow-cytometry
Figure 2. Exemplary flow cytometric analyis of PromoCell HDLEC. 99% of the cells are CD31 positive.
human-dermal-lymphatic-endothelial-cell-culture-flow-cytometry
Figure 2. Exemplary flow cytometric analyis of PromoCell HDLEC. 99% of the cells are CD31 positive.
Human Dermal Lymphatic Endothelial Cell Culture Flow cytometry podoplanin graph
Figure 3. Exemplary flow cytometric analysis of PromoCell HDLEC. 96% of the cells are podoplanin positive.
Human Dermal Lymphatic Endothelial Cell Culture Flow cytometry podoplanin graph
Figure 3. Exemplary flow cytometric analysis of PromoCell HDLEC. 96% of the cells are podoplanin positive.

Recommended Products