ROCKi is known to enhance the proliferation of epithelial cells or keratinocyte progenitors and can improve cell survival via conditional reprogramming and the effect is reversible. It is also known to enhance the seeding efficiency on plastic.
This ROCKi conditional reprogramming has also been observed in airway EpCs and cultured organoids:
https://pubmed.ncbi.nlm.nih.gov/31871466/
https://pubmed.ncbi.nlm.nih.gov/35169685/
For our human airway organoids,…
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