Human Dermal Microvascular Endothelial Cells (HDMEC)
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Primary Human Dermal Microvascular Endothelial Cells (HDMEC) are isolated from the dermis of juvenile foreskin and adult skin (different locations). Since the dermis contains blood and lymphatic capillaries, HDMEC comprise Blood and Lymphatic Microvascular Endothelial Cells. Both have a common origin and can be identified by several markers.
In addition, HDMEC are available which are pre-screened for VEGF (vascular endothelial growth factor) response. VEGF is an important signaling protein involved in both vasculogenesis and angiogenesis. In vitro, VEGF has been shown to stimulate endothelial cell mitogenesis, cell migration, sprouting, and microvascular permeability.
- Request our GMP grade cell culture media for endothelial cells.
- Our HDMEC (adult) are now also available from HLA-typed donors.
| Recommended plating density | 10,000 - 20,000 cells per cm2 |
| Passage after thawing | P2 |
| Tested markers | CD31 positive, Dil-Ac-LDL uptake positive |
| Guaranteed population doubling | > 15 |
| Recommended culture media* | C-22020,C-22022 |
*The catalog numbers in this table are for media in ready-to-use packaging.
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