HLA-Typed Human Primary Cells PromoCell offers a unique range of human leukocyte antigen (HLA)-typed cell donors. Choose from our large inventory and start your experiments immediately without time-consuming donor screenings. Why do you need HLA-typed cells? What do we offer? Available cell types The HLA system of cell-surface proteins regulates the human immune system and can be used as markers in research. A specific HLA type can be associated with an autoimmune disease (Mignot, Emmanuel, et al. 2001) or serve as a biomarker to show how cells respond to cancer treatments (Chowell et al. 2017). HLA types have also become important in understanding cardiovascular morbidity and mortality rates. Unlike animal testing, HLA-typed cells provide an optimal control system to test cancer reactive T-cells in a culture that represents the human system. With the rapid development of cancer immunotherapies such as adoptive cell therapy, custom cells screened for their HLA types are increasingly important for developing and testing new drugs. Key Advantages Minimize off-target interactions preclinically by testing translatability in a human cell setting. Better results than animal testing for the development and testing of new drugs. Buy with certainty your cells have the HLA type you need due to our HLA typing report – no need for further screening. Faster testing means shorter development time of new therapies for cancer patients. Test cross-reactivity of new therapies in multiple systems using our HLA-typed cells from lung, heart, kidney, or the cardiovascular system. Send us your request! Fill out our request form and let us know your donor requirements. Our team of scientific support specialists will be in touch to find the best solution for your research needs. A broad range of high-quality HLA-typed cells from several organs, allowing you to test potential therapies and detect cross-reactions. With more than 100 HLA-typed donors in stock and the complete HLA-typing certificate for each donor, save valuable time by cutting out your own primary cell HLA typing. Receive our Human Primary Cells and Blood and Stem Cells from an HLA-typed donor together with an HLA-Typing Certificate including 4-digit resolution typing for HLA-A, -B, -C, -DPA1/DPB1, -DQA1/DQB1, and -DRB1/DRB345. Matched donors available for multiple cell types. Only receive a donor with the HLA-type you wish to work with, no negative testing. Send us your request! Fill out our request form and let us know your donor requirements. Our team of scientific support specialists will be in touch to find the best solution for your research needs. Available HLA-typed human cells by tissue: Send us your request! Fill out our request form and let us know your donor requirements. Our team of scientific support specialists will be in touch to find the best solution for your research needs.
