The advantages of using primary cells in respiratory research
Respiratory research benefits from primary cell research as this biological niche has a complex array of cells influencing and acting upon each other. 3D cell culture using primary cells from a disease specific donor allows understanding of in vivo processes in disease specific states, and comparison to healthy donor cells. Learn more about the use of primary cells in respiratory research in our article….
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Cells that could lead to new therapies: PromoCell now offers in vitro disease models
– Portfolio extension: Wide range of donor cells with common chronic diseases
– New models can help researchers investigate disease development and find new treatment approaches
– Matched growth media are optimized for pharmaceutical drug discovery…
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Histocompatibility: Piecing together the immunotherapy puzzle
What do puzzles and immunity have in common? The human leukocyte antigen (HLA) system of cell-surface proteins help to regulate the immune system. Yet particular antigens can make a crucial difference. Patients with certain HLA types are more likely to have autoimmune diseases, contract infectious disease or develop cancer. Now, through better understanding of HLA function,…
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Keratinocytes
Definition and Location Keratinocytes represent the major cell type of the epidermis, the outermost of the layers of the skin, making up about 90 percent of the cells there. They originate in the deepest layer of the epidermis, the stratum basale and move up to the final barrier layer of the skin,…
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Clinically relevant cell culture tools for COVID-19 research
As the global COVID-19 pandemic evolves, researchers worldwide are working hard to study the mechanisms underlying SARS-CoV-2 infection. Thanks to their discoveries, new insights for developing treatments, vaccines and diagnostic tools are being made possible….
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Endothelial Cells
Definition Endothelial cells form the barrier between vessels and tissues (Aman et al., 2016). They control the flow of substances and fluid into and out of a tissue. An impaired function can lead to serious health issues throughout the body. Endothelial cells line blood vessels and lymphatic vessels, they are found exclusively in vascularized tissue (Bautch and Caron,…
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Discover our wide range of human blood cells
Are you developing cell and gene therapies or working in the field of immunology or immuno-oncology and are looking for high quality human blood cells? Discover more information on our range on our human blood cells flyer….
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Custom Solutions
Our custom services: Contact us via online form via email at custom.solutions@promocell.com or call +49 6221 649 34 0 to let us know your requirements. We’ll be more than happy to discuss the possibilities with you. Why PromoCell? Our support team, consisting of highly qualified PhD scientists, is devoted to providing you with the highest level of personalized service available in the market….
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HLA class II typed cells to accelerate effective research on immunotherapies
We support effective research on immunotherapies by expanding the range of HLA-types provided for all Human Primary Cells and Blood & Stem Cells. In addition to the MHC class I genes HLA-A, -B, and -C, we now also offer 4-digit resolution for MHC class II genes HLA-DPA1/DPB1, -DQA1/DQB1, and -DRB1/DRB345.
The Human Leukocyte Antigen (HLA) system plays a fundamental role in the determination of histocompatibility between different individuals and regulation of the human immunity….
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Understanding the vasculature with the help of HUVECs
Cells that feed other cells: The endothelium is a layer of cells that line blood vessels, and it is responsible for many tasks, including the transport of essential nutrients. Human umbilical vein endothelial cells (HUVECs) provide an in-vitro model for studying physiological and pathological processes of the vasculature.
“I’ll never forget the first time I added cancer cells to a HUVECs monolayer and watched them interact….
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Mesenchymal stem cells: why optimizing manufacturing processes is key for a successful application
Mesenchymal stem cells (MSCs) are the up-and-coming stars of cell therapy. They are able to differentiate, are very adaptable and can reduce inflammation, making them ideal for regenerative medicine approaches. But the demand for MSCs is far greater than supply. Pharmaceutical companies are racing to produce commercial-scale quantities of MSCs while guaranteeing quality standards….
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