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If I isolate tumor cells from my PDX animal model using your PCCS, will the animal cells survive?
In the Primary Cancer Culture System (PCCS, C‑28081), only
malignant tumor cells are supported.
As a result:
- Benign animal cells, such as fibroblasts, are not supported and are depleted under PCCS conditions.
- Malignant human tumor cells survive and can be maintained in culture.
This selective culture environment enables the enrichment of malignant human tumor cells while eliminating benign animal cell contamination.
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