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Human Dermal Lymphatic Endothelial Cells (HDLEC)

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Primary Human Dermal Lymphatic Endothelial Cells isolated from different sources (e.g. juvenile foreskin). CD31 and Dil-Ac-LDL uptake positive, Podoplanin positive.
Human Dermal Lymphatic Endothelial Cells (HDLEC)
Cat No IV-2441
Unit
913.00$
  • Adult donor
  • Juvenile donor
Ready to ship
Product description

Primary Human Dermal Lymphatic Endothelial Cells (HDLEC) are a subpopulation of the Human Dermal Endothelial Cells. They are isolated from the dermis of juvenile foreskin and adult skin (different locations) from a single donor.

Human Dermal Blood Endothelial Cells (HDBEC) from the same donor are available on request.

Lymphatic vessels transport excess fluids from tissues to the circulatory system and are a major component of the immune system. The transported fluid is nearly cell free. The vessels are highly permeable, because they lack a continuous basal membrane. Lymphatic endothelial cells are involved in pathological alterations of the lymphatic system. During tumor lymphangiogenesis, the lymphatic endothelial cells build new vessels that infiltrate tumors, attract tumor cells, and induce tumor cell metastasis.

Recommended plating density10,000 - 20,000 cells per cm2
Passage after thawingP2
Tested markersPodoplanin positive, CD31 positive, Dil-Ac-LDL uptake positive
Guaranteed population doubling> 15
Recommended culture media*C-22022

*The catalog numbers in this table are for media in ready-to-use packaging.
Data & figures
Figure 1.
Figure 1. Exemplary flow cytometric analyis of our HDLEC. 99% of the cells are CD31 positive.
Figure 2.
Figure 2. Exemplary flow cytometric analysis of our HDLEC. 96% of the cells are podoplanin positive.
Technical library
Resources
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