Why does PromoCell use CD146 as a marker for pericytes?
Description
CD146 (MUC18) is a surface marker expressed on pericytes MSCs and endothelial cells from large vessels (but not microvascular endothelial cells). In combination with CD34 (a marker for endothelial and hematopoietic cells) pericytes can be characterized by FACS analysis as CD146+/CD34-. The absence of CD34 expression makes sure that the cells are not of hematopoietic/endothelial origin. Further markers that have been described for pericytes are NG2 CD90 alpha-SMA and PDGFR-beta.