
3D Cell Culture
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We have developed a toolbox of cancer cell media to establish primary cancer cell lines from biopsies, develop 3D tumor models or build screening assays. Below you find the different application areas to discover solutions for your workflow and choose the right medium or combination of media to leverage your cancer research.
3D cancer model
An easy way to establish a 3D cancer model from cell line or biopsy. Use the media toolbox to establish assay panels for drug discovery and to develop complex 3D models.
Making best use of your PDX mouse
The PDX mouse is the working model for cancer therapies. The toolbox helps leveraging your PDX mouse project for better decision making and translation into clinic.
Cancer stem cell selection
Cancer stem cells (CSCs) are the tumor initiator and driver. Our toolbox conventiently selects CSCs and establishes healthy and defined patient-derived cancer cell lines.
From biopsy to assay
Are you working with patient-derived cancer cultures? Find out, how our toolbox helps you in setting up such cancer models and build advanced assays from your biopsy.
Extracellular vesicles in cancer
You are investigating EVs in cancer biology or using them in diagnostics or drug delivery? Our toolbox gives you an edge. Check out our EV-depleted and GMP-compliant media.
Immuno oncology
CAR-T and TCR cell therapies have seen the light of modern cancer treatment. Not only the T cell but also the proper cancer target cell, decide over the success in the clinic.
Tumor microenvironment
The TME has a significant impact on drug response in cancer therapies. With our toolbox you can set up a complex organoid model combining cancer and non-cancer cells.
CSC therapy
To effectively treat cancer, you need to target cancer stem cells (CSCs). Check out how our toolbox enables pure CSC isolation and expansion for advanced CSC therapy development.
The toolbox consists of three media, which all support and maintain cancer stem cells in a cancer cell culture. The choice of the medium allows to control, which additional types of cancer and non-cancer cells are supported or vice versa, which cell types will not grow in the medium. Depending on the medium and cancer type, 2D or 3D cell cultures can be generated.
Cancer stem cells share properties irrespectively of their origin such as self-renewal capability or anoikis resistance. Find more information, which properties we have chosen to design the unique features of our toolbox media.
A complete defined and animal-component free cell culture solution designed for the selective culture of malignant cells derived from primary tumors or patient-derived xenografts.
NCCD Reagent is part of our Primary Cancer Culture System and is crucial for the pre-treatment of the culture vessel.
Serum-free and xeno-free medium for the standardized in vitro cultivation of established cancer cell lines. Fibronectin or vitronectin coating required.