Optimizing cryopreservation: Serum-free cell freezing medium
Cryopreservation is an integral part of biomedical research and clinical applications. However, maintaining cell viability and function during freezing and thawing can be challenging. Serum-free cryopreservation media formulations are advanced solutions that can be used instead of serum-containing freezing media to maintain cell function while ensuring reproducibility and standardization — read on to learn why….
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Now available: Cryo-SFM Plus – The ultimate cryopreservation medium
Cryo-SFM Plus, our high-performance cryopreservation medium, is here! Find out how it can benefit your research….
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Extracellular vesicles in cancer therapy
EVs in tumor development Extracellular vesicles (EVs), including exosomes, play a crucial role in tumor biology. Alongside modulating the tumor microenvironment and contributing to the malignant cascade (angiogenesis, the host immune system response, and metastasis), EVs are involved in chemoresistance. Docetaxel in prostate cancer, for example, may transport mRNA encoding drug-resistant proteins or carry miRNA to recipient cells and trigger the expression of specific target genes….
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Privacy Policy
Proper protection of your personal data is a serious matter for PromoCell GmbH and we conform strictly to all data protection laws and regulations. The following declaration provides an overview of how we ensure this protection, as well as which types of data are collected and to what purpose. Scope of application This privacy statement informs users of the types,…
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Advancements and applications of tumor organoids in cancer research
Organoid models of patient-specific tumors are transforming our understanding of cancer heterogeneity and its implications for personalized medicine.
In this interview with BioTechniques, our experts, Janina Moros, Alexander Trampe and Zinnia Noor, discuss the benefits of tumor organoids, how to establish and culture them and their applications across different areas of cancer biology….
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Engineering a beating heart: The promise of cardiac spheroids
Innovative cardiac models are key to understanding heart diseases and finding new, potentially life-saving therapies. Bioprinting cardiac spheroids using primary human cells is a significant step toward creating a human beating heart in vitro. This article will explain why….
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Air-liquid interface culture: getting a closer look into our airways
Air-liquid interface culture (ALI) allow scientists to generate stable and functional in vitro 3D human airway cell models that closely mimic respiratory tract epithelia. With such models, researchers can investigate physiological and pathological processes of the respiratory tract. They can study interactions between epithelial cells and respiratory pathogens or air pollutants,…
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From biopsy to assay development
Struggling to get high quality biopsies? Isolating patient-derived cancer cells from different types of biopsies (bone marrow biopsy, core needle biopsy, endoscopic biopsy, etc.) is the golden standard for cancer research. However, obtaining regular surgical biopsies from patients is a challenging prospect. Additionally, the variability of the quality of tissue samples can be pretty high….
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Cell-based Manufacturing Media Platform
A GMP-compliant, customizable Manufacturing Media Platform (MMP) providing broad support for the serum-free culture of sophisticated cells used to manufacture cell-based products in a regulated environment. Currently the development of new therapeutic interventions often uses mammalian cells as an integral tool in the manufacturing process. However, the function of cells within these processes may differ substantially….
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EXCiPACT™ GMP certified produced cell culture media
A crucial step when developing new drugs and cell therapies and during development of new cosmetics or cell-based food production, is the translation of a technology from the research laboratory to clinical use in the real world, and subsequently commercial manufacturing. To ensure this step goes well, understanding and evaluating potential raw material risks of media and reagents is key when working with products in a regulated environment….
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3D skin model: The promise for dermatology
The development of 3D skin models has revolutionized in vitro studies in dermatology, offering a more representative platform for understanding skin structure and function in health and disease. In this article, we explain the biology of the human skin and explore the transformative potential of 3D skin models in reshaping our understanding of skin function….
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EV cancer treatment cell media: Importance and challenges
Since the birth of extracellular vesicle (EV) cancer treatment, EVs have provided invaluable biomarkers for cancer diagnosis and stable drug vehicles for treatment delivery. Correct isolation and suitable cell culture growth media are indispensable in producing effective, non-toxic EV cancer treatments….
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