For faster research on immunotherapies: HLA-typed human primary cells
– HLA-typed human primary cells for researchers across the world
– Great tool in the development and testing of new cancer drugs
– HLA-typed donor characteristics are precisely documented…
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EV cancer treatment cell media: Importance and challenges
Since the birth of extracellular vesicle (EV) cancer treatment, EVs have provided invaluable biomarkers for cancer diagnosis and stable drug vehicles for treatment delivery. Correct isolation and suitable cell culture growth media are indispensable in producing effective, non-toxic EV cancer treatments….
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Advancements and applications of tumor organoids in cancer research
Organoid models of patient-specific tumors are transforming our understanding of cancer heterogeneity and its implications for personalized medicine.
In this interview with BioTechniques, our experts, Janina Moros, Alexander Trampe and Zinnia Noor, discuss the benefits of tumor organoids, how to establish and culture them and their applications across different areas of cancer biology….
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Primary Cancer Cells: A Culture System Opens the Door to Individualized Therapy
Self-destruction of the body: Cancer turns normal body cells into their malignant counterpart that wants to keep on replicating by any means. Understanding the individual disease offers the potential for more effective therapies with fewer side effects. The new PromoCell Primary Cancer Culture System allows researchers to generate high-fidelity in vitro models of primary tumors….
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Studying oxidative stress and skin aging using in vitro human cell culture models
Oxidative stress results from an imbalance of pro- and anti-oxidants and leads to faster skin aging, inflammation and disease. Cell assays and primary cells provide the tools researchers need to study the oxidative process and its association with skin aging….
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Custom cell culture media solutions
Our custom cell culture media solutions include products that are tailored to your needs. We own our entire manufacturing process, so we can create customized products for clients in a huge range of markets worldwide. We empower scientists to conduct world-class research by offering an extensive portfolio of human primary cells,…
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Top tips for incorporating organoids into your research: expert interview
Our expert, Dr. Elfie Rödel, shares her top tips for incorporating organoids into your research in an interview with RegMedNet….
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Histocompatibility: Piecing together the immunotherapy puzzle
What do puzzles and immunity have in common? The human leukocyte antigen (HLA) system of cell-surface proteins help to regulate the immune system. Yet particular antigens can make a crucial difference. Patients with certain HLA types are more likely to have autoimmune diseases, contract infectious disease or develop cancer. Now, through better understanding of HLA function,…
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Tumor microenvironment
The role of CSCs and the TME Cellular interactions in the tumor microenvironment (TME) significantly influence cancer progression and drug response. The efficacy of immunotherapies has triggered increased interest in the tumor immune microenvironment. Therefore, robust experimental systems are needed to enable researchers to model patient-specific interactions between tumor cells and immune cells….
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Invisible attraction: Using magnets to develop drugs in cell cultures
Modern medicines are high-tech products. Developing medicines increasingly includes high throughput screening by fully automated analysis robots. One exciting high throughput approach uses magnetic 3D cell culture – which provides a more realistic model of human tissue than with 2D cell culture.
The later a candidate drops out, the more expensive it is….
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PDX mouse: Pushing the possibilities with ex vivo cell culture
Innovating mouse research such as PDX mouse models is key to improving cancer therapeutics. In translating scientific findings from mice to men, multiple techniques of collecting biological data are necessary. This article will explain how….
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A Home for Cancer Stem Cells: 3D Tumorspheres
Many scientists working in oncology focus on cancer stem cells (CSCs). Targeting these cells specifically could improve cancer therapy significantly. Because CSCs rely heavily on their environment, three-dimensional cultivation offers the unique opportunity to better understand this interaction. We talked to two scientists working in this field of cancer research.
In the human body,…
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