HLA class II typed cells to accelerate effective research on immunotherapies
We support effective research on immunotherapies by expanding the range of HLA-types provided for all Human Primary Cells and Blood & Stem Cells. In addition to the MHC class I genes HLA-A, -B, and -C, we now also offer 4-digit resolution for MHC class II genes HLA-DPA1/DPB1, -DQA1/DQB1, and -DRB1/DRB345.
The Human Leukocyte Antigen (HLA) system plays a fundamental role in the determination of histocompatibility between different individuals and regulation of the human immunity….
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Histocompatibility: Piecing together the immunotherapy puzzle
What do puzzles and immunity have in common? The human leukocyte antigen (HLA) system of cell-surface proteins help to regulate the immune system. Yet particular antigens can make a crucial difference. Patients with certain HLA types are more likely to have autoimmune diseases, contract infectious disease or develop cancer. Now, through better understanding of HLA function,…
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For faster research on immunotherapies: HLA-typed human primary cells
– HLA-typed human primary cells for researchers across the world
– Great tool in the development and testing of new cancer drugs
– HLA-typed donor characteristics are precisely documented…
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HLA-Typed Human Primary Cells
PromoCell offers a unique range of human leukocyte antigen (HLA)-typed cell donors. Choose from our large inventory and start your experiments immediately without time-consuming donor screenings….
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Could HLA-type be the answer to individual differences in COVID-19 severity?
The COVID-19 pandemic has changed the world. While vaccines are now being approved, a true understanding of the biological processes underlying COVID-19 and why some individuals develop severe disease while others are asymptomatic is necessary. HLA-type could be a key differentiator in disease outcomes, and in developing treatments….
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Discover our wide range of human blood cells
Are you developing cell and gene therapies or working in the field of immunology or immuno-oncology and are looking for high quality human blood cells? Discover more information on our range on our human blood cells flyer….
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Air-liquid interface culture: getting a closer look into our airways
Air-liquid interface culture (ALI) allow scientists to generate stable and functional in vitro 3D human airway cell models that closely mimic respiratory tract epithelia. With such models, researchers can investigate physiological and pathological processes of the respiratory tract. They can study interactions between epithelial cells and respiratory pathogens or air pollutants,…
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Custom Solutions
Our custom services: Contact us via online form via email at custom.solutions@promocell.com or call +49 6221 649 34 0 to let us know your requirements. We’ll be more than happy to discuss the possibilities with you. Why PromoCell? Our support team, consisting of highly qualified PhD scientists, is devoted to providing you with the highest level of personalized service available in the market….
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Cell expansion service
Our custom cell expansion service can be of great help in your research. Depending on the requirements of the field of your research (e.g., RNA-seq, high-throughput screening for drug discovery, toxicity screening for immunotherapy development), large numbers of primary cells are inevitable. Upscaling your cell culture in-house can be challenging for many reasons….
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Immuno-oncology
A new in vitro strategy Immuno-oncology is a unique combination of oncology and immunology. By activating or amplifying the body’s natural defenses, immuno-oncology aims to boost the immune system to fight cancer better. Targeted antibodies or immunomodulators are well-known immunotherapies; adoptive cell therapy using CAR-T or TCR cells is particularly important,…
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HLA-Typed Primary Cells: The advantages of working with HLA in drug development research
For those working in drug development, human leukocyte antigens or HLA are a key element to keep in mind as an essential regulator of the immune system….
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The importance of MSC characterization
Characterization of mesenchymal stem cells (MSCs) is vital for their successful application in regenerative medicine. These multipotent cells can differentiate into several cell types, making them a promising therapeutic option for various diseases. In our blog post, we discuss the importance of MSC characterization in ensuring standardized and reproducible cell isolation,…
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