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Search results for: 'research areas tumor microenvironment'

Items 1-12 of 132 Results

  • Advancements and applications of tumor organoids in cancer research

    Organoid models of patient-specific tumors are transforming our understanding of cancer heterogeneity and its implications for personalized medicine. In this interview with BioTechniques, our experts, Janina Moros, Alexander Trampe and Zinnia Noor, discuss the benefits of tumor organoids, how to establish and culture them and their applications across different areas of cancer biology…. Go To Page

  • PDX mouse: Pushing the possibilities with ex vivo cell culture

    Innovating mouse research such as PDX mouse models is key to improving cancer therapeutics. In translating scientific findings from mice to men, multiple techniques of collecting biological data are necessary. This article will explain how…. Go To Page

  • Cancer stem cells in tumor biology

    How do cancer stem cells develop? What is their role in tumor biology? What are current approaches to target cancer stem cells? And what are innovative solutions for working with them? Find all the answers in our blog post…. Go To Page

  • Teaching the body to fight tumors using cancer immunotherapy

    Selected as the 2013 “Breakthrough of the Year” by Science magazine, cancer immunotherapy shows a completely new way to treat malignancies by using the body’s own immune system, and not by targeting the tumor itself. This cutting-edge area of research and therapy has shown very promising results. However, further investigation is needed to turn immunotherapy into a cancer therapy that can be broadly applied…. Go To Page

  • Tumor microenvironment

    The role of CSCs and the TME Cellular interactions in the tumor microenvironment (TME) significantly influence cancer progression and drug response. The efficacy of immunotherapies has triggered increased interest in the tumor immune microenvironment. Therefore, robust experimental systems are needed to enable researchers to model patient-specific interactions between tumor cells and immune cells…. Go To Page

  • Primary Cancer Cells: A Culture System Opens the Door to Individualized Therapy

    Self-destruction of the body: Cancer turns normal body cells into their malignant counterpart that wants to keep on replicating by any means. Understanding the individual disease offers the potential for more effective therapies with fewer side effects. The new PromoCell Primary Cancer Culture System allows researchers to generate high-fidelity in vitro models of primary tumors…. Go To Page

  • Mesenchymal Stem Cells: Challenges and chances in cancer therapy

    As the potential for using mesenchymal stem cells in cancer therapy grows, understanding the biology behind them can help inform and inspire innovative cancer therapies. Using high quality media and culture kits will increase the efficiency and usability of these highly demanded cells.  … Go To Page

  • Tumor organoids – a new dimension in cancer research

    Tumor organoids offer a more accurate representation of the 3D tumor microenvironment, opening new avenues for cancer research and personalized medicine. However, establishing and maintaining tumor organoids can be more challenging than working with 2D cell cultures…. Go To Page

  • Cancer cell culture: Diversity of cells in the tumor microenvironment (TME)

    Tumor growth is sustained by a highly diverse microenvironment, the TME. Its complex cellular interactions need serious consideration during Cancer Research…. Go To Page

  • Applications for our cancer media toolbox

    We have developed a toolbox of cancer cell media to establish primary cancer cell lines from biopsies, develop 3D tumor models or build screening assays. Below you find the different application areas to discover solutions for your workflow and choose the right medium or combination of media to leverage your cancer research…. Go To Page

  • CSC therapy – towards new opportunities

    CSCs as therapeutic targets Cancer stem cells (CSCs) are a small subset of tumor cells that are able to evade anti-tumor defense mechanisms and suppress anti-tumor immune responses by releasing soluble immunosuppressive factors, such as anti-inflammatory cytokines. CSCs appear to have multiple strategies to escape immunological destruction, including the acquisition of genetic and non-genetic alterations that reduce immune recognition,… Go To Page

  • Immuno-oncology

    A new in vitro strategy Immuno-oncology is a unique combination of oncology and immunology. By activating or amplifying the body’s natural defenses, immuno-oncology aims to boost the immune system to fight cancer better. Targeted antibodies or immunomodulators are well-known immunotherapies; adoptive cell therapy using CAR-T or TCR cells is particularly important,… Go To Page

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