How Air-Liquid Interface (ALI) media compositions influence the epithelial barrier integrity
Selecting an appropriate medium is a crucial step to develop an ALI culture with a long-lasting barrier function. We provide the tools for a reliable epithelial barrier formation….
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Discover our Air-Liquid Interface (ALI) culture system
Our standardized Air-Liquid Interface (ALI) Medium in combination with ALI pre-screened Human Bronchial Epithelial Cells enables creation of a reproducible human 3D airway model with stable and predictable epithelial barrier function….
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Cell expansion service
Our custom cell expansion service can be of great help in your research. Depending on the requirements of the field of your research (e.g., RNA-seq, high-throughput screening for drug discovery, toxicity screening for immunotherapy development), large numbers of primary cells are inevitable. Upscaling your cell culture in-house can be challenging for many reasons….
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Privacy Policy
Proper protection of your personal data is a serious matter for PromoCell GmbH and we conform strictly to all data protection laws and regulations. The following declaration provides an overview of how we ensure this protection, as well as which types of data are collected and to what purpose. Scope of application This privacy statement informs users of the types,…
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Introducing a novel high throughput 3D wound healing model
Non-healing wounds continue to cause significant patient burden. This blog details a novel 3D wound healing model that promises to facilitate the development of new treatments to promote wound healing.
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Air-liquid interface culture: getting a closer look into our airways
Air-liquid interface culture (ALI) allow scientists to generate stable and functional in vitro 3D human airway cell models that closely mimic respiratory tract epithelia. With such models, researchers can investigate physiological and pathological processes of the respiratory tract. They can study interactions between epithelial cells and respiratory pathogens or air pollutants,…
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Trouble With Your Primary Cells? Treat Them Nicely!
What seems basic to cell culturing is pure stress for primary cells: thawing, subcultivation and freezing. Even seasoned scientists tend to overlook this aspect, and manipulate their cultures less carefully than they should. Unhealthy, or even dead cells are the sad consequence. Here, you can benefit from an expert’s tips in handling primary cells,…
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Malignant mesothelioma: Paving the way for new therapies
From bench to bedside and back: This is the direction of malignant mesothelioma research. Yet to understand the biology of this particular type of cancer, more basic insights are still needed. And translating that knowledge into new therapies is extremely important, as only limited therapeutic options exist so far.
Molecular needles that cross the lung epithelium: That’s how asbestos – often in form of dust – enters lung tissue (Carbone et al.,…
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Mesenchymal stem cells: why optimizing manufacturing processes is key for a successful application
Mesenchymal stem cells (MSCs) are the up-and-coming stars of cell therapy. They are able to differentiate, are very adaptable and can reduce inflammation, making them ideal for regenerative medicine approaches. But the demand for MSCs is far greater than supply. Pharmaceutical companies are racing to produce commercial-scale quantities of MSCs while guaranteeing quality standards….
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3D cancer model
De-skilling 3D tumor models Tissue-engineered 3D cancer models have grown in popularity with recent advances in cancer research. 3D models are more biomimetic than 2D cell monolayers cultured on tissue culture plastic. Examples are spheroids, tumorspheres, organoids, PDX and lately, tumoroids, which differ by origin (cell line or patient-derived), size, the complexity of cellular architecture and tumor environment….
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Why you should know your human mesenchymal stem cells inside out
Doctors, and patients with chronic diseases, are putting hope into new findings in regenerative medicine that are based on mesenchymal stem cell (MSC) research. As promising as some published results sound, they might be not reproducible – simply due to insufficient authentication and poor handling of cell cultures. Rigorous validation of cell identity is crucial for working with human mesenchymal stem cells – and,…
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Mesenchymal Stem Cells: Challenges and chances in cancer therapy
As the potential for using mesenchymal stem cells in cancer therapy grows, understanding the biology behind them can help inform and inspire innovative cancer therapies. Using high quality media and culture kits will increase the efficiency and usability of these highly demanded cells.
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