Macrophages Subtypes: Polarization, Activation and Plasticity
Macrophages Subtypes: Polarization, Activation and Plasticity
Macrophages are multitasking cells at the first line of defense against pathogens invasion. But they can also play a major role in destroying tissues and developing cancer, autoimmune disorder or allergies.
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Human M1 Macrophages (GM-CSF) monocyte-derived
Monocyte-derived, polarized, non-activated, primary human macrophages. Polarization in M1-Macrophage Generation Medium XF (incl. GM-CSF).
£1,336.00
Human M2 Macrophages (M-CSF) monocyte-derived
Monocyte-derived, polarized, non-activated, primary human macrophages. Polarization in M2-Macrophage Generation Medium XF (incl. M-CSF).
£1,336.00
M1-Macrophage Generation Medium XF
Serum-free and xeno-free medium for generation of M1 macrophages from fresh monocytes.
£590.00
M2-Macrophage Generation Medium XF
Serum-free and xeno-free medium for generation of M2 macrophages from fresh monocytes.
£590.00
Macrophage Base Medium XF
User-customizable, serum-free and xeno-free medium for generation of macrophages from fresh monocytes. Medium does not include cytokines.
£199.00
Related resources
Differentiation of M1- or M2-Macrophages from PBMC/Monocytes
Here we describe how the presence of PromoCell differentiation media encourages in vitro differentiation of mononcytes to macrophages. These then show either an M1-like or an M2-like polarization.
Application Note
Convenient Large-Scale Differentiation of Fully Customized Monocyte-Derived Macrophages From Human PBMC In Vitro
Primary human macrophages are difficult to isolate and do not proliferate in culture. PromoCell offers a complete system for easy and cost-efficient generation of pure monocyte-derived macrophages.
Application Note
Human Blood Cells Types
Discover our broad range of human blood cells, including macrophages, mononuclear cells from peripheral blood (PBMC) and cord blood, CD14+ monocytes, and CD34+ progenitor cells. Specific donor information like age, sex, and HLA-type is available for each produced lot.
Application Note
Macrophage Cell Culture
Discover PromoCell’s macrophage cell culture portfolio. This ranges from a media system for generating macrophages to assay-ready cryopreserved macrophages, as well as essential macrophage analysis tools.
Application Note
Macrophage polarization: plasticity in health and disease
Learn more about generating the whole macrophage spectrum in vitro and their role in health and disease.
Application Note