Macrophages Subtypes: Polarization, Activation and Plasticity
Macrophages Subtypes: Polarization, Activation and Plasticity
Macrophages are multitasking cells at the first line of defense against pathogens invasion. But they can also play a major role in destroying tissues and developing cancer, autoimmune disorder or allergies.
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![Human M1 Macrophages (GM-CSF) monocyte-derived](https://promocell.com/media/catalog/product/cache/8b767308ae356b7496032bdbcf598dd9/c/r/cryovial_10.jpg)
Human M1 Macrophages (GM-CSF) monocyte-derived
Monocyte-derived, polarized, non-activated, primary human macrophages. Polarization in M1-Macrophage Generation Medium XF (incl. GM-CSF).
€1,195.00
![Human M2 Macrophages (M-CSF) monocyte-derived](https://promocell.com/media/catalog/product/cache/8b767308ae356b7496032bdbcf598dd9/c/r/cryovial_1_1.jpg)
Human M2 Macrophages (M-CSF) monocyte-derived
Monocyte-derived, polarized, non-activated, primary human macrophages. Polarization in M2-Macrophage Generation Medium XF (incl. M-CSF).
€1,195.00
![M1-Macrophage Generation Medium XF](https://promocell.com/media/catalog/product/cache/8b767308ae356b7496032bdbcf598dd9/c/-/c-28055.jpg)
M1-Macrophage Generation Medium XF
Serum-free and xeno-free medium for generation of M1 macrophages from fresh monocytes.
€663.00
![M2-Macrophage Generation Medium XF](https://promocell.com/media/catalog/product/cache/8b767308ae356b7496032bdbcf598dd9/c/-/c-28056.jpg)
M2-Macrophage Generation Medium XF
Serum-free and xeno-free medium for generation of M2 macrophages from fresh monocytes.
€663.00
![Macrophage Base Medium XF](https://promocell.com/media/catalog/product/cache/8b767308ae356b7496032bdbcf598dd9/c/-/c-28057.jpg)
Macrophage Base Medium XF
User-customizable, serum-free and xeno-free medium for generation of macrophages from fresh monocytes. Medium does not include cytokines.
€197.00
Related resources
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Differentiation of M1- or M2-Macrophages from PBMC/Monocytes
Here we describe how the presence of PromoCell differentiation media encourages in vitro differentiation of mononcytes to macrophages. These then show either an M1-like or an M2-like polarization.
Application Note
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Convenient Large-Scale Differentiation of Fully Customized Monocyte-Derived Macrophages From Human PBMC In Vitro
Primary human macrophages are difficult to isolate and do not proliferate in culture. PromoCell offers a complete system for easy and cost-efficient generation of pure monocyte-derived macrophages.
Application Note
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Human Blood Cells Types
Discover our broad range of human blood cells, including macrophages, mononuclear cells from peripheral blood (PBMC) and cord blood, CD14+ monocytes, and CD34+ progenitor cells. Specific donor information like age, sex, and HLA-type is available for each produced lot.
Application Note
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Macrophage Cell Culture
Discover PromoCell’s macrophage cell culture portfolio. This ranges from a media system for generating macrophages to assay-ready cryopreserved macrophages, as well as essential macrophage analysis tools.
Application Note
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Macrophage polarization: plasticity in health and disease
Learn more about generating the whole macrophage spectrum in vitro and their role in health and disease.
Application Note