What is the difference between “primary cells” and “normal cells”?
Normal cells are primary cells that have been subcultured at least once. From this point onward (i.e. passage ≥ 1), they should correctly be termed normal cells.
In summary, the distinction is purely based on culture history and passage number, not on cell origin or biological characteristics.
In everyday laboratory practice, however, the term “primary cells” is often used interchangeably with “normal cells".
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