What are the criteria for selection or exclusion of peripheral blood donors? Is the peripheral blood used by PromoCell to isolate blood cells (MNC‑PB, monocytes) derived from completely healthy donors?

Peripheral blood used by PromoCell for the isolation of mononuclear cells from peripheral blood (MNC‑PB) and monocytes is obtained from carefully screened donors. A defined set of selection and exclusion criteria is applied prior to blood donation.
 
Donor exclusion criteria
The following conditions lead to temporary or permanent exclusion from blood donation:
a) Acute infections
- Mild infections (e.g. cold or cough): exclusion for 1 week
- Infections with body temperature > 37.9°C and/or antibiotic treatment: exclusion for 4 weeks
b) Blood pressure
- Exclusion if:
  systolic blood pressure < 100 mm Hg or > 180 mm Hg, or
  diastolic blood pressure > 100 mm Hg
- No exclusion if blood pressure is medically treated and within an acceptable range
c) Metabolic conditions
- High cholesterol: no exclusion, even if medication is used
- Diabetes: exclusion in cases of type I diabetes or insulin therapy
d) Medication use
- Steroid treatment: exclusion for 4 weeks after application
e) Severe or chronic diseases
- Cancer: exclusion
- Other chronic diseases: exclusion depends on the specific condition (e.g. chronic heart disease, autoimmune diseases)