EXCiPACT™ GMP certified produced cell culture media
A crucial step when developing new drugs and cell therapies and during development of new cosmetics or cell-based food production, is the translation of a technology from the research laboratory to clinical use in the real world, and subsequently commercial manufacturing. To ensure this step goes well, understanding and evaluating potential raw material risks of media and reagents is key when working with products in a regulated environment….
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Introducing a novel high throughput 3D wound healing model
Non-healing wounds continue to cause significant patient burden. This blog details a novel 3D wound healing model that promises to facilitate the development of new treatments to promote wound healing.
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Now available: Cryo-SFM Plus – The ultimate cryopreservation medium
Cryo-SFM Plus, our high-performance cryopreservation medium, is here! Find out how it can benefit your research….
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Cancer stem cells in tumor biology
How do cancer stem cells develop? What is their role in tumor biology? What are current approaches to target cancer stem cells? And what are innovative solutions for working with them? Find all the answers in our blog post….
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Endothelial Cells
Definition Endothelial cells form the barrier between vessels and tissues (Aman et al., 2016). They control the flow of substances and fluid into and out of a tissue. An impaired function can lead to serious health issues throughout the body. Endothelial cells line blood vessels and lymphatic vessels, they are found exclusively in vascularized tissue (Bautch and Caron,…
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The importance of MSC characterization
Characterization of mesenchymal stem cells (MSCs) is vital for their successful application in regenerative medicine. These multipotent cells can differentiate into several cell types, making them a promising therapeutic option for various diseases. In our blog post, we discuss the importance of MSC characterization in ensuring standardized and reproducible cell isolation,…
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Disclaimer
Disclaimer 1. Online-contents PromoCell GmbH reserves the right not to be responsible for the topicality, correctness, completeness or quality of the information provided. Liability claims regarding damage caused by the use of any information provided, including any kind of information which is incomplete or incorrect, will therefore be rejected. All offers are not-binding and without obligation….
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Cellular agriculture – the livestock farms of the future?
“Fifty years hence, we shall escape the absurdity of growing a whole chicken in order to eat the breast or wing by growing these parts separately under a suitable medium.” Winston Churchill, 1931. It may have taken us more than fifty years, but we are getting closer to Churchill’s dream of producing meat-like food without needing a live animal….
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How Air-Liquid Interface (ALI) media compositions influence the epithelial barrier integrity
Selecting an appropriate medium is a crucial step to develop an ALI culture with a long-lasting barrier function. We provide the tools for a reliable epithelial barrier formation….
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Using 3D Skin Models to Test Cosmetics
Skin is the primary focus of cosmetic research. Since the European Union banned animal testing of cosmetics completely in 2013, three-dimensional skin models have been used to evaluate epidermal and dermal responses to cosmetic formulations. Such models provide a reliable tool to assess the functionality and safety of new cosmetic products….
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Super-resolution microscopy: Zooming in on the eorld of the influenza A virus
It adapts quickly to the cellular defense mechanisms of the host and develops resistance against antiviral drugs: The influenza A virus is a major human pathogen with high variability. New super-resolution microscopy methods, as well as the use of human primary cells, currently allow better insights into the interactions between viruses and host cells….
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Making best use of your PDX mouse
Transfer from PDX to in vitro assays Xenograft models are extensively used to provide information about the safety and efficacy in drug development, especially for targeted cancer therapies. Patient-derived xenograft (PDX) mice are the preferred mouse tumor models, but cell line-derived xenografts (CDXs) and nude rat xenografts are also used. Nevertheless,…
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