Mycoplasma is the nightmare of every scientist working with Cell Culture. Mycoplasma contamination is threatening academic labs to biopharmaceutical production facilities. Dr. Rüdiger Arnold explains why best practice in detection, elimination and avoiding mycoplasma are necessary for your cell culture….
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Mycoplasma contamination – small organisms cause big trouble
An invisible enemy that reduces the growth rate of your cell lines, mycoplasma threaten your hard work and scientific data. Every fourth cell culture could be affected. But there is hope. Our expert, Dr. Tobi Limke, explains how you can prevent mycoplasma contamination, and she outlines ways to deal with bacteria once they have infiltrated your plates and flasks….
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Optimizing cryopreservation: Serum-free cell freezing medium
Cryopreservation is an integral part of biomedical research and clinical applications. However, maintaining cell viability and function during freezing and thawing can be challenging. Serum-free cryopreservation media formulations are advanced solutions that can be used instead of serum-containing freezing media to maintain cell function while ensuring reproducibility and standardization — read on to learn why….
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Stem cell immunotherapy: Harnessing the immune system
Imagine a future where diseases once considered incurable are now within reach of treatment. This is the promise of stem cell immunotherapy, a rapidly evolving approach that harnesses the unique properties of pluripotent cells to revolutionize medical treatments.1 From autoimmune diseases to cancer, the potential of stem cell immunotherapy is vast and transformative. …
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Keratinocytes
Definition and Location Keratinocytes represent the major cell type of the epidermis, the outermost of the layers of the skin, making up about 90 percent of the cells there. They originate in the deepest layer of the epidermis, the stratum basale and move up to the final barrier layer of the skin,…
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EXCiPACT™ GMP certified produced cell culture media
A crucial step when developing new drugs and cell therapies and during development of new cosmetics or cell-based food production, is the translation of a technology from the research laboratory to clinical use in the real world, and subsequently commercial manufacturing. To ensure this step goes well, understanding and evaluating potential raw material risks of media and reagents is key when working with products in a regulated environment….
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GMP grade cell culture – infographic and expert interview
Good manufacturing practice (GMP) guidelines are particularly important for the media and reagents used in the development and manufacture of cell therapies. Gain expert insight and download our comprehensive infographic….
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Using 3D Skin Models to Test Cosmetics
Skin is the primary focus of cosmetic research. Since the European Union banned animal testing of cosmetics completely in 2013, three-dimensional skin models have been used to evaluate epidermal and dermal responses to cosmetic formulations. Such models provide a reliable tool to assess the functionality and safety of new cosmetic products….
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EV cancer treatment cell media: Importance and challenges
Since the birth of extracellular vesicle (EV) cancer treatment, EVs have provided invaluable biomarkers for cancer diagnosis and stable drug vehicles for treatment delivery. Correct isolation and suitable cell culture growth media are indispensable in producing effective, non-toxic EV cancer treatments….
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Now available: PromoExQ MSC Growth Medium XF suitable for GMP applications
We are proud to offer our new PromoExQ MSC Growth Medium XF manufactured in compliance with the EXCiPACT™ GMP certification standard, including relevant supporting documentation at hand….
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Making best use of your PDX mouse
Transfer from PDX to in vitro assays Xenograft models are extensively used to provide information about the safety and efficacy in drug development, especially for targeted cancer therapies. Patient-derived xenograft (PDX) mice are the preferred mouse tumor models, but cell line-derived xenografts (CDXs) and nude rat xenografts are also used. Nevertheless,…
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Custom cell culture media solutions
Our custom cell culture media solutions include products that are tailored to your needs. We own our entire manufacturing process, so we can create customized products for clients in a huge range of markets worldwide. We empower scientists to conduct world-class research by offering an extensive portfolio of human primary cells,…
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