Clinically relevant cell culture tools for COVID-19 research
As the global COVID-19 pandemic evolves, researchers worldwide are working hard to study the mechanisms underlying SARS-CoV-2 infection. Thanks to their discoveries, new insights for developing treatments, vaccines and diagnostic tools are being made possible….
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Could HLA-type be the answer to individual differences in COVID-19 severity?
The COVID-19 pandemic has changed the world. While vaccines are now being approved, a true understanding of the biological processes underlying COVID-19 and why some individuals develop severe disease while others are asymptomatic is necessary. HLA-type could be a key differentiator in disease outcomes, and in developing treatments….
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For faster research on immunotherapies: HLA-typed human primary cells
– HLA-typed human primary cells for researchers across the world
– Great tool in the development and testing of new cancer drugs
– HLA-typed donor characteristics are precisely documented…
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The advantages of using primary cells in respiratory research
Respiratory research benefits from primary cell research as this biological niche has a complex array of cells influencing and acting upon each other. 3D cell culture using primary cells from a disease specific donor allows understanding of in vivo processes in disease specific states, and comparison to healthy donor cells. Learn more about the use of primary cells in respiratory research in our article….
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PromoCell announces services for large-scale industrial lots of Mesenchymal Stem Cells
– New services for large-scale industrial lots allows customers to have high volumes of standardized MSC populations derived from bone marrow and adipose tissue
– Guaranteed MSC functionality and phenotype in accordance to ISCT* guidelines
– Optimized media with complete supplementation and expert technical support…
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CRISPR/Cas9: The Genome Editing Revolution
The genetic code is the blueprint of an organism written on a stable molecule class: deoxyribonucleic acid. With the method CRISPR/Cas9, editing the genetic information has become much easier. This technique is a blessing for basic scientists, as well as for translational researchers such as Dr. Kathleen Börner, who wants to develop a gene therapy for infections caused by human immunodeficiency virus (HIV)….
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Finding new targets for diabetes drug development using in vitro cell assays
Diabetes is a global healthcare problem with a growing prevalence. The disease is systemic, leading to reduced quality of life if untreated. A myriad of assays and research tools are available to study the disease and find effective treatments….
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COVID-19 Research
Leading virology labs and pharmaceutical companies around the globe rely on PromoCell products for developing new strategies to fight COVID-19….
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Malignant mesothelioma: Paving the way for new therapies
From bench to bedside and back: This is the direction of malignant mesothelioma research. Yet to understand the biology of this particular type of cancer, more basic insights are still needed. And translating that knowledge into new therapies is extremely important, as only limited therapeutic options exist so far.
Molecular needles that cross the lung epithelium: That’s how asbestos – often in form of dust – enters lung tissue (Carbone et al.,…
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Teaching the body to fight tumors using cancer immunotherapy
Selected as the 2013 “Breakthrough of the Year” by Science magazine, cancer immunotherapy shows a completely new way to treat malignancies by using the body’s own immune system, and not by targeting the tumor itself. This cutting-edge area of research and therapy has shown very promising results. However, further investigation is needed to turn immunotherapy into a cancer therapy that can be broadly applied….
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Cancer stem cells in tumor biology
How do cancer stem cells develop? What is their role in tumor biology? What are current approaches to target cancer stem cells? And what are innovative solutions for working with them? Find all the answers in our blog post….
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Understanding the vasculature with the help of HUVECs
Cells that feed other cells: The endothelium is a layer of cells that line blood vessels, and it is responsible for many tasks, including the transport of essential nutrients. Human umbilical vein endothelial cells (HUVECs) provide an in-vitro model for studying physiological and pathological processes of the vasculature.
“I’ll never forget the first time I added cancer cells to a HUVECs monolayer and watched them interact….
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