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Search results for: 'blog studying oxidative stress and skin aging using in vitro human cell culture models'

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  • Studying oxidative stress and skin aging using in vitro human cell culture models

    Oxidative stress results from an imbalance of pro- and anti-oxidants and leads to faster skin aging, inflammation and disease. Cell assays and primary cells provide the tools researchers need to study the oxidative process and its association with skin aging…. Go To Page

  • Using 3D Skin Models to Test Cosmetics

    Skin is the primary focus of cosmetic research. Since the European Union banned animal testing of cosmetics completely in 2013, three-dimensional skin models have been used to evaluate epidermal and dermal responses to cosmetic formulations. Such models provide a reliable tool to assess the functionality and safety of new cosmetic products…. Go To Page

  • Introducing a novel high throughput 3D wound healing model

    Non-healing wounds continue to cause significant patient burden. This blog details a novel 3D wound healing model that promises to facilitate the development of new treatments to promote wound healing.  … Go To Page

  • Finding new targets for diabetes drug development using in vitro cell assays

    Diabetes is a global healthcare problem with a growing prevalence. The disease is systemic, leading to reduced quality of life if untreated. A myriad of assays and research tools are available to study the disease and find effective treatments…. Go To Page

  • 3D skin model: The promise for dermatology

    The development of 3D skin models has revolutionized in vitro studies in dermatology, offering a more representative platform for understanding skin structure and function in health and disease. In this article, we explain the biology of the human skin and explore the transformative potential of 3D skin models in reshaping our understanding of skin function…. Go To Page

  • Endothelial Cells

    Definition Endothelial cells form the barrier between vessels and tissues (Aman et al., 2016). They control the flow of substances and fluid into and out of a tissue. An impaired function can lead to serious health issues throughout the body. Endothelial cells line blood vessels and lymphatic vessels, they are found exclusively in vascularized tissue (Bautch and Caron,… Go To Page

  • Mimicking the body’s largest organ in vitro with 3D skin models

    Researchers are increasingly using 3D cell cultures to study the skin’s features. Three-dimensional skin models offer the potential to study various diseases and test compounds in vitro. Dr. Florian Groeber-Becker from the Fraunhofer Institute for Silicate Research ISC in Wurzburg has developed a highly sophisticated skin model. It is the first thing people see when they look at us…. Go To Page

  • How Oxygen Affects Primary Cell Culture

    Oxygen has two faces: While it’s a life-saving gas essential for humans and animals, excessive generation of reactive oxygen species damages cells and promotes senescence. This duality is the research focus of Professor Giovanni E. Mann of King’s College London. Prof. Mann and his colleagues are currently investigating redox signaling in vascular cells in culture…. Go To Page

  • Adipocytes: key players in metabolic homeostasis

    Adipocytes do more than simply store fat. They also play a role in metabolic diseases. Through better understanding of how adipose cells function and interact, researchers can develop new, targeted therapies for treating adipositas and diabetes. Our bodies and the bodies of all living organisms work like batteries: we get energy from food,… Go To Page

  • Keratinocytes

    Definition and Location Keratinocytes represent the major cell type of the epidermis, the outermost of the layers of the skin, making up about 90 percent of the cells there. They originate in the deepest layer of the epidermis, the stratum basale and move up to the final barrier layer of the skin,… Go To Page

  • Invisible attraction: Using magnets to develop drugs in cell cultures

    Modern medicines are high-tech products. Developing medicines increasingly includes high throughput screening by fully automated analysis robots. One exciting high throughput approach uses magnetic 3D cell culture – which provides a more realistic model of human tissue than with 2D cell culture. The later a candidate drops out, the more expensive it is…. Go To Page

  • 15 cell culture facts: Things about cell culture you might not know

    As a researcher working in cell culture, you must have a deep understanding of your specific research area. However, scientific knowledge is advancing rapidly. Therefore, keeping up with all the developments in cell-based research can be challenging. In this article, we present 15 facts about cell culture that can add to your knowledge…. Go To Page

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