Why does PromoCell use CD146 as a marker for pericytes?
CD146 (also known as MUC18) is a surface marker that is expressed on pericytes, but it can also be found on mesenchymal stem cells (MSCs) and endothelial cells from large vessels. Importantly, microvascular endothelial cells do not express CD146.
Marker combination for pericyte identification
To reliably distinguish pericytes from other cell types, CD146 is used in combination with CD34:
Additional pericyte markers
Other markers that have been described for pericytes in the literature include NG2, CD90, α‑smooth muscle actin (α‑SMA), PDGFR‑β.
Please note: These markers are not part of PromoCell's routine Quality Control (QC) testing for pericytes and are therefore not included in the lot-specific Certificate of Analysis (CoA).
Marker combination for pericyte identification
To reliably distinguish pericytes from other cell types, CD146 is used in combination with CD34:
- Pericytes: CD146⁺ / CD34⁻
- Endothelial and hematopoietic cells: CD34⁺
Additional pericyte markers
Other markers that have been described for pericytes in the literature include NG2, CD90, α‑smooth muscle actin (α‑SMA), PDGFR‑β.
Please note: These markers are not part of PromoCell's routine Quality Control (QC) testing for pericytes and are therefore not included in the lot-specific Certificate of Analysis (CoA).
