The immunomodulatory properties of mesenchymal stem cells (MSCs)
Since their discovery in 1991, mesenchymal stem cells, or MSCs, have been used as a promising method to build tissue. However, MSCs can do more for the development of cell and gene therapies. Find out more in our video. With the latest research, our understanding of the mechanisms induced by MSCs in therapeutic applications has shifted: MSCs also provide therapeutic benefits in the host body via paracrine effects and the stimulation of host cells, as they can modulate the innate and adaptive immune responses. Indeed, MSCs not only serve as tissue progenitor cells, but they also have the ability to alter the tissue environment. How does this work to result in a therapeutic potential? Learn more in our video.
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Human Mesenchymal Stem Cells (hMSC), Cell Pellet in RNAlater
Cell pellet of hMSC from adipose tissue, bone marrow and umbilical cord matrix in RNAlater® for subsequent RNA, DNA or protein analysis.
Mesenchymal Stem Cell Chondrogenic Differentiation Medium
Serum-free cell culture medium for differentiation of mesenchymal cells into chondrogenic lineages.
Mesenchymal Stem Cell Growth Medium 2
Low-serum cell growth medium for mesenchymal stems cells.
Human Mesenchymal Stem Cells (hMSC)
Primary Human Mesenchymal Stem Cells. Available from adipose tissue, bone marrow and umbilical cord matrix.Related resources
Neurogenic Differentiation and Analysis of Mesenchymal Stem Cells (MSC)
Specific culture conditions allow for transdifferentiation of mesenchymal stem cells (MSC) into cells of non-mesenchymal origin such as neurons. To do so, specific culture conditions and stimuli are needed.
Application Note
Chondrogenic Differentiation and Analysis of Mesenchymal Stem Cells (MSC)
Managed in vitro differentiation of mesenchymal stem cells (MSC) into chondrocytes. Multipotent adult stem cells are important for various tissues of the musculoskeletal system.
Application Note
Adipogenic Differentiation and Analysis of Mesenchymal Stem Cells (MSC)
Turning mesenchymal stem cells (MSC) into adipocytes is the aim of this application note. Research using MSC is a field of high interest and could ultimately lead to new therapies for treating a variety of lifestyle diseases.
Application Note
Xeno-free MSC culture: high yield, better viability and morphology
Are you trying to mimic in vivo conditions in your MSC cultures as closely as possible, but need to avoid serum? Then find out how the combination of PromoCell DXF medium and a unique coating called myMATRIX help you make your conditions highly physiological while maintaining reproducibility.
Application Note
MSC cultivation in single-use stirred tank bioreactors
MSCs have gained significant attention because of their therapeutic potential for many difficult-to-treat diseases. In this app note, we provide a protocol for (GMP) compliant large-scale production of MSCs in a single-use bioreactor using our MSC Growth Medium XF.
Application Note
Metabolic Activity During Mesenchymal Stem cell (MSC) Differentiation
Detailed analysis of human stem cells offers the potential for the specific treatment of diseases by cell-based therapies. With an automated real-time analysis, we assess phenotypic changes during mesenchymal stem cell (MSC) differentiation.
Application Note
Mesenchymal stem cells: a cell culture handbook
Discover key insights into MSC cell culture, emphasizing the importance of media selection for cell therapy applications.
Application Note
Osteogenic Differentiation and Analysis of Mesenchymal Stem Cells (MSC)
Differentiate mesenchymal stem cells (MSC) into osteoblasts. Read our application note and find out more. The multipotency of these cells is one essential characteristic of MSC, according to the International Society for Cellular Therapy.
Application Note