Accelerating pre-clinical research with the use of HLA-typed primary cells
In this webinar (~30 min) Dr. Manish Kumar (Product Manager, Cells & Media at PromoCell) will touch base on HLA genetics, its typing, nomenclature and HLA applications in pre-clinical research.…
Go To Page
HLA-Typed Primary Cells: The advantages of working with HLA in drug development research
For those working in drug development, human leukocyte antigens or HLA are a key element to keep in mind as an essential regulator of the immune system….
Go To Page
HLA class II typed cells to accelerate effective research on immunotherapies
We support effective research on immunotherapies by expanding the range of HLA-types provided for all Human Primary Cells and Blood & Stem Cells. In addition to the MHC class I genes HLA-A, -B, and -C, we now also offer 4-digit resolution for MHC class II genes HLA-DPA1/DPB1, -DQA1/DQB1, and -DRB1/DRB345.
The Human Leukocyte Antigen (HLA) system plays a fundamental role in the determination of histocompatibility between different individuals and regulation of the human immunity….
Go To Page
Stem cell therapy scientist: Finding inspiration outside his comfort zone
Crossing the border between medical and biomechanical research fuels the research of stem cell specialist Dr. Diego Correa. We talked to the Colombian-born stem cell scientist, a former clinician with training in mechanical engineering, about his studies with mesenchymal stem cells and their potential clinical applications in cell-based therapy. Soon Correa is going to publish what he believes will be his most important contribution to this field….
Go To Page
Immuno-oncology
A new in vitro strategy Immuno-oncology is a unique combination of oncology and immunology. By activating or amplifying the body’s natural defenses, immuno-oncology aims to boost the immune system to fight cancer better. Targeted antibodies or immunomodulators are well-known immunotherapies; adoptive cell therapy using CAR-T or TCR cells is particularly important,…
Go To Page
Air-liquid interface culture: getting a closer look into our airways
Air-liquid interface culture (ALI) allow scientists to generate stable and functional in vitro 3D human airway cell models that closely mimic respiratory tract epithelia. With such models, researchers can investigate physiological and pathological processes of the respiratory tract. They can study interactions between epithelial cells and respiratory pathogens or air pollutants,…
Go To Page
The importance of MSC characterization
Characterization of mesenchymal stem cells (MSCs) is vital for their successful application in regenerative medicine. These multipotent cells can differentiate into several cell types, making them a promising therapeutic option for various diseases. In our blog post, we discuss the importance of MSC characterization in ensuring standardized and reproducible cell isolation,…
Go To Page
Branching out: In vitro angiogenesis advancements
In this interview with RegMedNet, our expert, Iris Bischoff-Kont, discusses the latest advancements in angiogenesis research and their potential applications in regenerative medicine. Dr Bischoff-Kont also explores the challenges faced in translating angiogenesis research findings into clinical therapies and the importance of understanding the crosstalk between angiogenesis and other processes like inflammation….
Go To Page
Clinically relevant cell culture tools for COVID-19 research
As the global COVID-19 pandemic evolves, researchers worldwide are working hard to study the mechanisms underlying SARS-CoV-2 infection. Thanks to their discoveries, new insights for developing treatments, vaccines and diagnostic tools are being made possible….
Go To Page
Discover our Air-Liquid Interface (ALI) culture system
Our standardized Air-Liquid Interface (ALI) Medium in combination with ALI pre-screened Human Bronchial Epithelial Cells enables creation of a reproducible human 3D airway model with stable and predictable epithelial barrier function….
Go To Page
Invisible attraction: Using magnets to develop drugs in cell cultures
Modern medicines are high-tech products. Developing medicines increasingly includes high throughput screening by fully automated analysis robots. One exciting high throughput approach uses magnetic 3D cell culture – which provides a more realistic model of human tissue than with 2D cell culture.
The later a candidate drops out, the more expensive it is….
Go To Page
The advantages of using primary cells in respiratory research
Respiratory research benefits from primary cell research as this biological niche has a complex array of cells influencing and acting upon each other. 3D cell culture using primary cells from a disease specific donor allows understanding of in vivo processes in disease specific states, and comparison to healthy donor cells. Learn more about the use of primary cells in respiratory research in our article….
Go To Page