Getting started with primary cells – Standard procedures in cell culture
In this quick start guide, we review the finer points of thawing, plating, and passaging primary human cells. Even if you’re experienced using these cells, we review some of the little things that can make a large difference in your cell culture success with our cells. Presented by PromoCell Application Specialist,…
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Thawing frozen cells – detailed protocol for human primary cells
Thawing cells correctly is absolutely necessary when it comes to successfully starting reliable cell cultures. Find out how to thaw frozen primary cells properly in our detailed video protocol….
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Air-liquid interface culture: getting a closer look into our airways
Air-liquid interface culture (ALI) allow scientists to generate stable and functional in vitro 3D human airway cell models that closely mimic respiratory tract epithelia. With such models, researchers can investigate physiological and pathological processes of the respiratory tract. They can study interactions between epithelial cells and respiratory pathogens or air pollutants,…
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Five Steps to Writing a Great Scientific Article
Thousands of scientific articles are published each year. It’s a basic series of steps in biomedical research: do experiments, analyze data, publish your results, and repeat. It seems straightforward, but one question remains. How do you write a paper for publication if it’s your first one?
A blank white page, and a silently blinking cursor: How can an empty document be so intimidating?…
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Compliance
Our commitment to quality To do great research, you need high-quality products you can trust. That’s why we’ve put quality and reliability at the heart of our business for over 30 years. Our portfolio includes over 400 human cell culture products including primary cells, stem cells, blood cells, and optimized cell growth and differentiation media….
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Stem cell therapy scientist: Finding inspiration outside his comfort zone
Crossing the border between medical and biomechanical research fuels the research of stem cell specialist Dr. Diego Correa. We talked to the Colombian-born stem cell scientist, a former clinician with training in mechanical engineering, about his studies with mesenchymal stem cells and their potential clinical applications in cell-based therapy. Soon Correa is going to publish what he believes will be his most important contribution to this field….
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3D cancer model
De-skilling 3D tumor models Tissue-engineered 3D cancer models have grown in popularity with recent advances in cancer research. 3D models are more biomimetic than 2D cell monolayers cultured on tissue culture plastic. Examples are spheroids, tumorspheres, organoids, PDX and lately, tumoroids, which differ by origin (cell line or patient-derived), size, the complexity of cellular architecture and tumor environment….
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Cancer stem cell selection
Advance cancer stem cell culture Cancer stem cells (CSCs) are a specific and small subpopulation of tumor cells. Despite their low number, they drive tumor initiation, influence tumor progression, and cause metastasis and relapse. Increased cancer stem cell populations have been shown to reflect the aggressiveness and therapy-resistant phenotype of the tumor….
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Invisible attraction: Using magnets to develop drugs in cell cultures
Modern medicines are high-tech products. Developing medicines increasingly includes high throughput screening by fully automated analysis robots. One exciting high throughput approach uses magnetic 3D cell culture – which provides a more realistic model of human tissue than with 2D cell culture.
The later a candidate drops out, the more expensive it is….
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EXCiPACT™ GMP certified produced cell culture media
A crucial step when developing new drugs and cell therapies and during development of new cosmetics or cell-based food production, is the translation of a technology from the research laboratory to clinical use in the real world, and subsequently commercial manufacturing. To ensure this step goes well, understanding and evaluating potential raw material risks of media and reagents is key when working with products in a regulated environment….
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Macrophage plasticity is more than black and white
Many rules in biology exist, and even more exceptions to these rules. For years, immunologists have tried to classify macrophages into two subtypes, classically activated M1, and alternatively activated M2 macrophages. However, with the growing number of activated macrophage subtypes needing description, established nomenclature falls short. Researchers are seeking an alternative to the traditional black-and-white principle….
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Starting with 3D cell culture
Making use of 3D cell culture can give you access to new and powerful in vitro models that model the in vivo environment. In this overview, you’ll be introduced to the main methods in 3D culture and how best to use them in your research….
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