How Air-Liquid Interface (ALI) media compositions influence the epithelial barrier integrity
Selecting an appropriate medium is a crucial step to develop an ALI culture with a long-lasting barrier function. We provide the tools for a reliable epithelial barrier formation….
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Air-liquid interface culture: getting a closer look into our airways
Air-liquid interface culture (ALI) allow scientists to generate stable and functional in vitro 3D human airway cell models that closely mimic respiratory tract epithelia. With such models, researchers can investigate physiological and pathological processes of the respiratory tract. They can study interactions between epithelial cells and respiratory pathogens or air pollutants,…
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Discover our Air-Liquid Interface (ALI) culture system
Our standardized Air-Liquid Interface (ALI) Medium in combination with ALI pre-screened Human Bronchial Epithelial Cells enables creation of a reproducible human 3D airway model with stable and predictable epithelial barrier function….
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Top tips for incorporating organoids into your research: expert interview
Our expert, Dr. Elfie Rödel, shares her top tips for incorporating organoids into your research in an interview with RegMedNet….
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Primary cells in respiratory research – webinar
Learn about the benefits of primary cells as model systems in respiratory research and how a 3D model at the Air-Liquid Interface can be set up and used….
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Tissue engineering of the respiratory epithelium: insights in culture methods and applications
This webinar addresses both interested beginners as well as advanced scientists in the field and focuses on key issues like cell sources, air liquid interface (ALI) culture, medium demands and current challenges regarding reproducibility and standardization.
In vitro culture of primary respiratory epithelial cells has constantly gained influence in disease modeling and is moreover basis for functional tissue engineering of the airways….
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Create a 3D human airway model with air-liquid interface culture
Generation of a 3D human airway model with primary human nasal and tracheal epithelial cells using our Air-Liquid Interface Medium (ALI-Airway)….
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The advantages of using primary cells in respiratory research
Respiratory research benefits from primary cell research as this biological niche has a complex array of cells influencing and acting upon each other. 3D cell culture using primary cells from a disease specific donor allows understanding of in vivo processes in disease specific states, and comparison to healthy donor cells. Learn more about the use of primary cells in respiratory research in our article….
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Accelerating regenerative medicine with air-liquid interface (ALI) technology
Gain expert insights into the increasing relevance of ALI in regenerative medicine from our in-depth interview featured on RegMedNet….
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Clinically relevant cell culture tools for COVID-19 research
As the global COVID-19 pandemic evolves, researchers worldwide are working hard to study the mechanisms underlying SARS-CoV-2 infection. Thanks to their discoveries, new insights for developing treatments, vaccines and diagnostic tools are being made possible….
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Mimicking the body’s largest organ in vitro with 3D skin models
Researchers are increasingly using 3D cell cultures to study the skin’s features. Three-dimensional skin models offer the potential to study various diseases and test compounds in vitro. Dr. Florian Groeber-Becker from the Fraunhofer Institute for Silicate Research ISC in Wurzburg has developed a highly sophisticated skin model.
It is the first thing people see when they look at us….
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Antibiotics in Cell Culture: Friend or Enemy?
Antibiotics are routinely used in cell cultures to prevent bacterial infections. But there are side effects: Studies show that they impair cell growth and differentiation. With good laboratory practice, the use of antibiotics is unnecessary.
A cell culture is a world of its own. The culture dish contains nutrients within the media that cells need to thrive and prosper….
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