Respiratory pathways such as glycolysis, the tricarboxylic acid (TCA) cycle, and the mitochondrial electron transport chain are essential for cellular energy and various physiological functions throughout nature. Glycolysis is a crucial biological mechanism, allowing cells to gain access to the energy they need. This means the enzymes of the glycolytic pathway are potential targets in cancer therapy and diabetes….
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Super-resolution microscopy: Zooming in on the eorld of the influenza A virus
It adapts quickly to the cellular defense mechanisms of the host and develops resistance against antiviral drugs: The influenza A virus is a major human pathogen with high variability. New super-resolution microscopy methods, as well as the use of human primary cells, currently allow better insights into the interactions between viruses and host cells….
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From disease to healing: Exploring the roles of pericytes
They are multipotent, interact closely with endothelial cells, and are involved in immunosurveillance: the heterogeneous group of pericytes. These cells build the wall of blood vessels, and play a crucial role in the formation and maintenance of the vasculature. Due to their involvement in various pathophysiologies such as tumor angiogenesis, scientists are beginning to exploit their potential for therapeutic approaches….
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Macrophage plasticity is more than black and white
Many rules in biology exist, and even more exceptions to these rules. For years, immunologists have tried to classify macrophages into two subtypes, classically activated M1, and alternatively activated M2 macrophages. However, with the growing number of activated macrophage subtypes needing description, established nomenclature falls short. Researchers are seeking an alternative to the traditional black-and-white principle….
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Primary Cancer Cells: A Culture System Opens the Door to Individualized Therapy
Self-destruction of the body: Cancer turns normal body cells into their malignant counterpart that wants to keep on replicating by any means. Understanding the individual disease offers the potential for more effective therapies with fewer side effects. The new PromoCell Primary Cancer Culture System allows researchers to generate high-fidelity in vitro models of primary tumors….
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Understanding the vasculature with the help of HUVECs
Cells that feed other cells: The endothelium is a layer of cells that line blood vessels, and it is responsible for many tasks, including the transport of essential nutrients. Human umbilical vein endothelial cells (HUVECs) provide an in-vitro model for studying physiological and pathological processes of the vasculature.
“I’ll never forget the first time I added cancer cells to a HUVECs monolayer and watched them interact….
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Compliance
Our commitment to quality To do great research, you need high-quality products you can trust. That’s why we’ve put quality and reliability at the heart of our business for over 30 years. Our portfolio includes over 400 human cell culture products including primary cells, stem cells, blood cells, and optimized cell growth and differentiation media….
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Cellular agriculture – the livestock farms of the future?
“Fifty years hence, we shall escape the absurdity of growing a whole chicken in order to eat the breast or wing by growing these parts separately under a suitable medium.” Winston Churchill, 1931. It may have taken us more than fifty years, but we are getting closer to Churchill’s dream of producing meat-like food without needing a live animal….
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Privacy Policy
Proper protection of your personal data is a serious matter for PromoCell GmbH and we conform strictly to all data protection laws and regulations. The following declaration provides an overview of how we ensure this protection, as well as which types of data are collected and to what purpose. Scope of application This privacy statement informs users of the types,…
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