Growing stem cells in space – PromoCell aboard the International Space Station
In March 2020, two researchers at the University of Zurich (UZH) Space Hub, Professor Oliver Ullrich and Dr. Cora Thiel, sent human stem cells to space to determine if they could develop into three-dimensional organoids. Three years later, the results of this and a subsequent experiment demonstrate that culturing stem cells in space is possible,…
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PromoCells in space continues – producing human tissue in a weightless environment
Two research leaders from the University of Zurich (UZH) Space Hub, Professor Oliver Ullrich and Dr. Cora Thiel, have sent adult human stem cells to the International Space Station (ISS). They are testing an innovative method to produce human tissue in a weightless environment, and hope to better understand how human tissue is produced in the weightless atmosphere of space….
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15 cell culture facts: Things about cell culture you might not know
As a researcher working in cell culture, you must have a deep understanding of your specific research area. However, scientific knowledge is advancing rapidly. Therefore, keeping up with all the developments in cell-based research can be challenging. In this article, we present 15 facts about cell culture that can add to your knowledge….
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PromoCells in Space – Ready For Lift-Off
Three, Two, One, Zero: Two research groups working in space life sciences are investigating the behavior of cells from PromoCell in microgravity on the International Space Station. The launch of a Falcon 9 rocket coupled to a Dragon spacecraft is planned for December 15th in Florida, USA.
Gravity is everywhere on earth,…
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Rocket science: The mystery of how macrophages adapt in space
In recent decades, many in vitro studies with living human cells have broadened our knowledge about the cellular and molecular effects of microgravity. Cells of the immune system are particularly sensitive to it and represent an ideal model for understanding how space flight could affect cell function. Prof. Ullrich and his team have greatly contributed to explaining how cells behave in space….
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Cells in Action: Human Primary Keratinocytes at the stratum granulosum
Keratinocytes at the stratum granulosum contain two characteristic structures that are visible in this high resolution footage by Nanolive – the lamellar bodies and keratohyalin granules. While keratohyalin granules contain proteins involved in the aggregation of keratin filaments and in the formation of the cell envelope, lamellar bodies contain lipids and fuse with the plasma membrane in order to secrete the content into the extracellular space….
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PromoCell now exclusive supplier of MATra (Magnet-Assisted Transfection)
Primary cells can prove much more difficult to transfect than other commonly used cell lines. While high transfection efficiencies are possible using commercially available transfection reagents in diverse, commonly used cell lines, primary cells but also diverse cell lines have proven much more difficult to transfect….
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From disease to healing: Exploring the roles of pericytes
They are multipotent, interact closely with endothelial cells, and are involved in immunosurveillance: the heterogeneous group of pericytes. These cells build the wall of blood vessels, and play a crucial role in the formation and maintenance of the vasculature. Due to their involvement in various pathophysiologies such as tumor angiogenesis, scientists are beginning to exploit their potential for therapeutic approaches….
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PromoCell announces services for large-scale industrial lots of Mesenchymal Stem Cells
– New services for large-scale industrial lots allows customers to have high volumes of standardized MSC populations derived from bone marrow and adipose tissue
– Guaranteed MSC functionality and phenotype in accordance to ISCT* guidelines
– Optimized media with complete supplementation and expert technical support…
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EV cancer treatment cell media: Importance and challenges
Since the birth of extracellular vesicle (EV) cancer treatment, EVs have provided invaluable biomarkers for cancer diagnosis and stable drug vehicles for treatment delivery. Correct isolation and suitable cell culture growth media are indispensable in producing effective, non-toxic EV cancer treatments….
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The importance of MSC characterization
Characterization of mesenchymal stem cells (MSCs) is vital for their successful application in regenerative medicine. These multipotent cells can differentiate into several cell types, making them a promising therapeutic option for various diseases. In our blog post, we discuss the importance of MSC characterization in ensuring standardized and reproducible cell isolation,…
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Why you should know your human mesenchymal stem cells inside out
Doctors, and patients with chronic diseases, are putting hope into new findings in regenerative medicine that are based on mesenchymal stem cell (MSC) research. As promising as some published results sound, they might be not reproducible – simply due to insufficient authentication and poor handling of cell cultures. Rigorous validation of cell identity is crucial for working with human mesenchymal stem cells – and,…
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