Items 1-12 of 98 Results
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Cells in Action: Human Primary Keratinocytes at the stratum granulosum
Keratinocytes at the stratum granulosum contain two characteristic structures that are visible in this high resolution footage by Nanolive - the lamellar bodies and keratohyalin granules. While keratohyalin granules contain proteins involved in the aggregation of keratin filaments and in the formation of the cell envelope, lamellar bodies contain lipids and fuse with the plasma membrane in order to secrete the content into the extracellular space. -
Isolation of patient-derived primary cancer cells
Isolate tumor cells from patient samples and transform them into long-term cell cultures. Learn more about the primary cancer culture system and how it compares to other established culture methods. -
Primary cancer cell culture from human tumor samples
Learn more about the Primary Cancer Culture System and how it compares to other established culture methods. -
Depletion of benign cells from established cancer cell cultures with the PromoCell Primary Cancer Culture System D-ACF
Traditional culture systems for cancer cells all share a lack of specific growth support for malignant cells. PromoCell's Primary Cancer Culture System is a reliable tool for depleting stromal cells, fibroblasts, and all other types of non-cancerous cells. -
Cancer Cell Culture
Our cancer cell culture portfolio covers a complete range of applications for culturing human malignant cells. Download our brochure to find out more. -
Cancer cell culture: Diversity of cells in the tumor microenvironment (TME)
Tumor growth is sustained by a highly diverse microenvironment, the TME. Its complex cellular interactions need serious consideration during Cancer Research. -
Obtain Pure Malignant Cells with the New Cancer Cell Culture Toolkit
The new cancer cell culture toolkit from PromoCell aids the growth of both primary tumors as well as established cells lines, explains Dr. Hagen Wieland during the AACR (American Association for Cancer Research) Annual Meeting in Chicago. -
Growing cancer organoids
Cancer organoids or tumorspheres? Our infographic will help you find the right model for your research. -
The importance of HLA for the development of cell therapies
Download our white paper to understand the role Human Leukocyte Antigen plays in the development of cell therapies. -
Cells in action: Differentiation of human mesenchymal stem cells into neurons
Cells in action: Differentiation of human mesenchymal stem cells into neurons In this video we can see the differentiation of PromoCell umbilical cord mesenchymal stem cells into neurons. Excitingly, to our knowledge this is one of the first high-resolution, long-term, live cell time-lapses showing this process. These cells were grown for 13 days in PromoCell complete mesenchymal stem cell neurogenic differentiation medium prior to capture of this film. Images were captured every 30 seconds over a 20-hour period using NanoLive’s 3D Cell Explorer. -
Cells in Action: membrane protrusions in HUVECs (Human Umbilical Vein Endothelial Cells)
During angiogenesis, cell-matrix interactions are crucial. The cell matrix structures are involved in migration, invasion and survival of cells throughout the angiogenic process. In this video we can see filopodia and lamellipodia in great detail, thanks to Nanolive imaging's ability to view membrane deformations. These structures are essential for migration, cell-cell interactions, sensing of the cell environment and more. While filopodia appear as long, thin protrusion-like structures that emerge from the cellular membrane, lamellipodia are broad, sheet-shaped structures containing thin and short interconnected actin filaments. -
Cells in Action: Double mitosis of Human Umbilical Vein Endothelial Cells (HUVECs)
Images of cells undergoing mitosis are mind-blowing, and non more beautiful than those of our Human Umbilical Vein Endothelial Cells (HUVECs) captured by Nanolive's 3D Cell Explorer. On the right hand side, the cell seems to enter mitosis but the chromatids don't complete segregation and the cell returns to interphase without dividing. Exiting mitosis is controlled by proteolysis and cyclin dependent kinases (CDKs). Mitosis regulatory machinery sometimes detects errors and forces a return to interphase, as seen here. This kind of research helps develop understanding of the cell cycle, which can be used in myriad applications including cancer research.