I have noticed that Cryo-SFM Plus has a strong odor and turns yellow when frozen. Is this normal?

Yes. Both the distinct odor and the color change are normal characteristics of Cryo-SFM Plus and are caused by the antioxidant technology used in the freezing medium. These properties do not affect cell performance and pose no risk to the user or the cells.
 
Background: Cryo-SFM Plus contains a proprietary antioxidant system designed to enhance post-thaw cell viability, attachment, and growth.
 
Please note:

• Frozen Cryo-SFM Plus appears yellow
• After thawing, the medium turns orange
• Cryo-SFM Plus does not turn pink