Do PromoCell HDMECs exhibit migration and tube formation in response to angiogenic stimuli?

In principle, all microvascular endothelial cells, including human dermal microvascular endothelial cells (HDMEC), should be able to migrate, proliferate, and form tubes or sprouts in appropriate angiogenesis assays after stimulation with angiogenic factors.
 
Limitations of routine quality control
Migration and tube formation assays are not part of PromoCell’s routine quality control.
Therefore, we cannot guarantee that every HDMEC lot will respond uniformly to angiogenic stimuli.
 
Pre‑screened option
For applications where a defined angiogenic response is critical, PromoCell offers:

• HDMEC pre‑screened for VEGF-responsiveness (C‑12215)

These cells are specifically tested for a positive response to VEGF, providing greater confidence for angiogenesis‑focused assays.