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Why are the cryopreserved macrophages abbreviated as hMDM-GMCSF(-) and hMDM-MCSF(-) respectively? What does the (-) stand for?

Description
  • hMDM-GMCSF is the abbreviation for human monocyte-derived macrophages. They are polarized [⇒ differentiated with GM-CSF] but non-activated [⇒ (-)] M1 macrophages
  • hMDM-MCSF is the abbreviation for human monocyte-derived polarized [⇒ differentiated with M-CSF] but non-activated [⇒ (-)] M2 macrophages
The macrophages can be seeded into all kinds of TC vessels. After plating; they can be maintained as biologically functional adherent cultures for several weeks.Optionally; user-customizable activation of the cells can be performed. For details; please see attached Application Note; page 2; Fig. 3 and page 5; Tab. 1).
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