Human Cardiac Myocytes (HCM)
Our Primary Human Cardiac Myocytes (HCM) are isolated from the ventricles of the adult heart. They are qualified for in vitro research on cardiac diseases and for pharmacological studies. Our HCM behave like progenitor cells and are not fully differentiated. They do not spontaneously beat in vitro, but unlike freshly isolated rod-shaped myocytes, our HCM can be cultured for at least 15 population doublings. Therefore, when cultured in our Myocyte Growth Medium, HCM are suitable for long-term experiments like investigating the long-term effects of cytokines, toxicological screenings, or cell-cell interactions.
- Request our GMP grade cell culture media for cardiac myocytes.
- Our HCM are now also available from HLA-typed and Diabetes Type I and Type II/Cardiomypathy donors.
| Recommended plating density | 10000 - 15000 cells per cm2 |
| Passage after thawing | P2 |
| Tested markers | GATA-4 positive, sarcomeric α-actin positive |
| Guaranteed population doubling | > 15 |
Note: We have updated the marker profile used for the quality control of our Human Cardiac Myocytes due to a reassessment of the specification profile of our cells. From now on, our cells will be tested positive for GATA-4 and sarcomeric α-actin instead of being tested positive for sarcomeric α-actinin and slow muscle myosin. Please note that all other product specifications remain unchanged. For details, please refer to the Certificate of Analysis or get in contact with us: [email protected]

