The importance of HLA for the development of cell therapies
Download our white paper to understand the role Human Leukocyte Antigen plays in the development of cell therapies.
The HLA complex plays a critical role in human immunity, notably in cell therapy. As translational research is gaining momentum, understanding the interplay between HLA and cancer is becoming increasingly relevant.
In this white paper, our expert Product Manager Dr. Lisa Hamelmann will guide you through the following topics:
- HLA restriction: finding and binding
- HLA and diseases: activating autoimmune responses
- HLA and cancer: how cancer cells escape recognition
- New therapeutic options: harnessing HLA for cancer immunotherapy
- HLA-typed cells: an important control system to test new immunotherapies
Download the white paper
Fill in the form to download the PDF.
Related resources
HLA-Typed Primary Cells: The advantages of working with HLA in drug development research
For those working in drug development, human leukocyte antigens or HLA are a key element to keep in mind as an essential regulator of the immune system. Watch our latest explainer video to understand the benefits of working with HLA in your pre-clinical research.
Application Note
HLA molecules in cancer: Balancing the fine line between cure and collateral
Learn how human leukocyte antigen (HLA) molecules are playing crucial roles in cancer.
Application Note
The human leukocyte antigen (HLA) complex
Learn more about HLA - The human leukocyte antigen complex and its role in the immune system.
Application Note
Recommended products
Human Umbilical Artery Endothelial Cells (HUAEC)
Primary Human Umbilical Endothelial Cells isolated from the arteries of the umbilical cord.
1’172.00 CHF
Human Pulmonary Artery Smooth Muscle Cells (HPASMC)
Primary Human Pulmonary Artery Smooth Muscle Cells isolated from human pulmonary arteries.
1’918.00 CHF
Human Pulmonary Fibroblasts (HPF)
Primary Human Pulmonary Fibroblasts isolated from human lung tissue.
1’337.00 CHF
Human Pulmonary Microvascular Endothelial Cells (HPMEC)
Primary Human Pulmonary Microvascular Endothelial Cells isolated from the lung from a single donor.
1’882.00 CHF
Human Renal Cortical Epithelial Cells (HRCEpC)
Primary Human Renal Cortical Epithelial Cells isolated from the cortex of the human kidney.
1’917.00 CHF
Human Renal Epithelial Cells (HREpC)
Primary Human Renal Epithelial Cells isolated from the adult kidney.
1’550.00 CHF
Human Saphenous Vein Endothelial Cells (HSaVEC)
Primary Human Saphenous Vein Endothelial Cells isolated from saphenous veins from single donors.
1’518.00 CHF
Human Skeletal Muscle Cells (SkMC)
Primary Human Skeletal Muscle Cells isolated from different skeletal muscles from adult single donors.
1’697.00 CHF
Normal Human Epidermal Keratinocytes (NHEK)
Primary Human Keratinocytes isolated from the epidermis of juvenile foreskin or adult skin from single or pooled donors.
From
675.00 CHF
Human Small Airway Epithelial Cells (HSAEpC)
Primary Human Small Airway Epithelial Cells isolated from the human distal respiratory tract.
1’921.00 CHF
Human Tracheal Epithelial Cells (HTEpC)
Primary Human Tracheal Epithelial Cells isolated from surface epithelium of human trachea.
1’903.00 CHF
Human Tracheal Smooth Muscle Cells (HTSMC)
Primary Human Tracheal Smooth Muscle Cells isolated from the trachea from single donors.
1’829.00 CHF
Human Pulmonary Artery Endothelial Cells (HPAEC)
Primary human endothelial cells isolated from human pulmonary arteries.
1’892.00 CHF
Human Umbilical Artery Smooth Muscle Cells (HUASMC)
Primary Human Umbilical Artery Smooth Muscle Cells isolated from the arteries of the umbilical cord.
1’429.00 CHF
Human Umbilical Vein Endothelial Cells (HUVEC)
Primary Human Umbilical Vein Endothelial Cells isolated from the vein of the umbilical cord of single, pooled or pre-screened donors.
From
438.00 CHF
Human Umbilical Vein Endothelial Cells 2 (HUVEC 2)
HUVEC isolated from the umbilical vein of single, pooled or pre-screened donors in Endothelial Cell Growth Medium 2 containing additional VEGF.
From
454.00 CHF
Human Uterine Fibroblasts (HUF)
Primary Human Uterine Fibroblasts isolated from the uterine wall.
1’263.00 CHF
Human Uterine Microvascular Endothelial Cells (HUtMEC)
Primary Human Uterine Microvascular Endothelial Cells isolated from the myometrium from single donors. Donors not pre-treated with hormones.
1’843.00 CHF
Human Uterine Smooth Muscle Cells (HUtSMC)
Primary Human Uterine Smooth Muscle Cells isolated from the myometrium.
1’960.00 CHF
Human White Preadipocytes (HWP)
Primary Human White Preadipocytes are isolated from adult subcutaneous or visceral adipose tissue.
From
990.00 CHF
Normal Human Dermal Fibroblasts (NHDF)
Primary Normal Human Dermal Fibroblasts isolated from the dermis of juvenile foreskin or adult skin.
From
667.00 CHF
Normal Human Epidermal Keratinocytes (NHEK) GM3
Primary Human Keratinocytes isolated in serum-free and BPE-free Keratinocyte Growth Medium 3. Available from juvenile foreskin or adult skin from single or pooled donors.
From
675.00 CHF
Normal Human Epidermal Melanocytes (NHEM)
Primary Human Epidermal Melanocytes isolated in PMA-containing Melanocyte Growth Medium from the epidermis of juvenile foreskin.
906.00 CHF
Normal Human Epidermal Melanocytes M3 (NHEM M3)
Primary human epidermal melanocytes isolated in PMA-free Melanocyte Growth Medium M3. Available from juvenile and adult donors.
From
1’086.00 CHF
Human Pericytes from Placenta (hPC-PL)
Human Pericytes isolated from human placenta tissue.
1’650.00 CHF
Human Cardiac Myocytes (HCM)
Primary Human Cardiac Myocytes isolated from the ventricles of the adult heart.
1’860.00 CHF
Human CD14+ Monocytes (hMoCD14+-PB)
Human CD14+ Monocytes isolated from peripheral blood (hMoCD14+-PB) of single donors.
1’517.00 CHF
Human CD34+ Progenitor Cells (hCD34+-CB)
Human CD34+ Progenitor Cells from Cord Blood (hCD34+ -CB) of a single donor.
1’064.00 CHF
Human Chondrocytes (HCH)
Primary Human Chondrocytes isolated from normal human articular cartilage from the knee and hip joints.
1’894.00 CHF
Human Coronary Artery Endothelial Cells (HCAEC)
Primary Human Endothelial Cells isolated from the human coronary arteries from single donors.
1’880.00 CHF
Human Coronary Artery Smooth Muscle Cells (HCASMC)
Human Smooth Muscle Cells isolated from the human coronary arteries.
1’861.00 CHF
Human Dermal Blood Endothelial Cells (HDBEC)
Primary Human Dermal Blood Endothelial Cells isolated from different sources (e.g. juvenile foreskin). CD31 positive, Podoplanin negative.
From
1’551.00 CHF
Human Dermal Lymphatic Endothelial Cells (HDLEC)
Primary Human Dermal Lymphatic Endothelial Cells isolated from different sources (e.g. juvenile foreskin). CD31 positive, Podoplanin positive.
From
1’371.00 CHF
Human Dermal Microvascular Endothelial Cells (HDMEC)
Primary Human Dermal Microvascular Endothelial Cells isolated from the dermis of juvenile foreskin and adult skin.
From
1’562.00 CHF
Human M1 Macrophages (GM-CSF) monocyte-derived
Monocyte-derived, polarized, non-activated, primary human macrophages. Polarization in M1-Macrophage Generation Medium XF (incl. GM-CSF).
From
1’434.00 CHF
Human M2 Macrophages (M-CSF) monocyte-derived
Monocyte-derived, polarized, non-activated, primary human macrophages. Polarization in M2-Macrophage Generation Medium XF (incl. M-CSF).
From
1’434.00 CHF
Human Mesenchymal Stem Cells (hMSC)
Primary Human Mesenchymal Stem Cells. Available from adipose tissue, bone marrow and umbilical cord matrix.
From
1’651.00 CHF
Human Mononuclear Cells (hMNC)
Primary Human Mononuclear Cells isolated from umbilical cord blood and peripheral blood.
From
1’100.00 CHF
Human Nasal Epithelial Cells (HNEpC)
Primary Human Nasal Epithelial Cells isolated from normal human nasal mucosa.
1’639.00 CHF
Human Osteoblasts (HOB)
Primary Human Osteoblasts isolated from femoral trabecular bone tissue from the knee or hip joint region.
1’205.00 CHF
Human Aortic Adventitial Fibroblasts (HAoAF)
Primary Human Aortic Adventitial Fibroblasts isolated from the human aortic adventitial tissue.
1’667.00 CHF
Human Cardiac Microvascular Endothelial Cells (HCMEC)
Primary Human Cardiac Microvascular Endothelial Cells isolated from heart ventricles from single donors.
1’418.00 CHF
Human Cardiac Fibroblasts (HCF)
Primary Human Cardiac Fibroblasts isolated from the ventricles of the adult heart.
1’633.00 CHF
Human Bronchial Smooth Muscle Cells (HBSMC)
Human Bronchial Smooth Muscle Cells isolated from the human bronchi from single donors.
1’949.00 CHF
Human Bronchial Epithelial Cells (HBEpC)
Primary Human Bronchial Epithelial Cells isolated from the surface epithelium of human bronchi.
1’853.00 CHF
Human Aortic Smooth Muscle Cells (HAoSMC)
Primary Human Aortic Smooth Muscle Cells isolated from the human aorta.
1’838.00 CHF
Human Aortic Endothelial Cells (HAoEC)
Primary Human Aortic Endothelial Cells isolated from the human ascending and descending aorta.
1’834.00 CHF