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Search results for: 'blog introducing a novel high throughput 3d wound healing model'

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  • Introducing a novel high throughput 3D wound healing model

    Non-healing wounds continue to cause significant patient burden. This blog details a novel 3D wound healing model that promises to facilitate the development of new treatments to promote wound healing.  … Go To Page

  • 3D skin model: The promise for dermatology

    The development of 3D skin models has revolutionized in vitro studies in dermatology, offering a more representative platform for understanding skin structure and function in health and disease. In this article, we explain the biology of the human skin and explore the transformative potential of 3D skin models in reshaping our understanding of skin function…. Go To Page

  • Branching out: In vitro angiogenesis advancements

    In this interview with RegMedNet, our expert, Iris Bischoff-Kont, discusses the latest advancements in angiogenesis research and their potential applications in regenerative medicine. Dr Bischoff-Kont also explores the challenges faced in translating angiogenesis research findings into clinical therapies and the importance of understanding the crosstalk between angiogenesis and other processes like inflammation…. Go To Page

  • Mimicking the body’s largest organ in vitro with 3D skin models

    Researchers are increasingly using 3D cell cultures to study the skin’s features. Three-dimensional skin models offer the potential to study various diseases and test compounds in vitro. Dr. Florian Groeber-Becker from the Fraunhofer Institute for Silicate Research ISC in Wurzburg has developed a highly sophisticated skin model. It is the first thing people see when they look at us…. Go To Page

  • Studying oxidative stress and skin aging using in vitro human cell culture models

    Oxidative stress results from an imbalance of pro- and anti-oxidants and leads to faster skin aging, inflammation and disease. Cell assays and primary cells provide the tools researchers need to study the oxidative process and its association with skin aging…. Go To Page

  • Using 3D Skin Models to Test Cosmetics

    Skin is the primary focus of cosmetic research. Since the European Union banned animal testing of cosmetics completely in 2013, three-dimensional skin models have been used to evaluate epidermal and dermal responses to cosmetic formulations. Such models provide a reliable tool to assess the functionality and safety of new cosmetic products…. Go To Page

  • New application note: Wound healing assay kinetic analysis

    CytoSMART and PromoCell demonstrate how a wound healing assay can be easily performed with primary human keratinocytes using software-based data analysis to achieve more accurate results…. Go To Page

  • Understanding the vasculature with the help of HUVECs

    Cells that feed other cells: The endothelium is a layer of cells that line blood vessels, and it is responsible for many tasks, including the transport of essential nutrients. Human umbilical vein endothelial cells (HUVECs) provide an in-vitro model for studying physiological and pathological processes of the vasculature. “I’ll never forget the first time I added cancer cells to a HUVECs monolayer and watched them interact…. Go To Page

  • A young scientist seeks a method to knock out fibrosis

    Lab work is exciting, says Bastian Fischer. Even experiments that just yield their expected results inspire the young German scientist. Fischer is currently working on his PhD, and is investigating how fibrosis develops, so that effective therapies for this medical condition can be found. A scar is often all that remains of a deep cut – if anything remains at all…. Go To Page

  • PDX mouse: Pushing the possibilities with ex vivo cell culture

    Innovating mouse research such as PDX mouse models is key to improving cancer therapeutics. In translating scientific findings from mice to men, multiple techniques of collecting biological data are necessary. This article will explain how…. Go To Page

  • Tumor microenvironment

    The role of CSCs and the TME Cellular interactions in the tumor microenvironment (TME) significantly influence cancer progression and drug response. The efficacy of immunotherapies has triggered increased interest in the tumor immune microenvironment. Therefore, robust experimental systems are needed to enable researchers to model patient-specific interactions between tumor cells and immune cells…. Go To Page

  • Keratinocytes

    Definition and Location Keratinocytes represent the major cell type of the epidermis, the outermost of the layers of the skin, making up about 90 percent of the cells there. They originate in the deepest layer of the epidermis, the stratum basale and move up to the final barrier layer of the skin,… Go To Page

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