Characterization of mesenchymal stem cells (MSCs) is vital for their successful application in regenerative medicine. These multipotent cells can differentiate into several cell types, making them a promising therapeutic option for various diseases. In our blog post, we discuss the importance of MSC characterization in ensuring standardized and reproducible cell isolation,…
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Infographic: How do mesenchymal stem cells work?
Standardized mesenchymal stem cells are essential to carrying out reproducible research. In our detailed infographic you will learn about the importance of MSC characterization (including cell surface antigens), isolation, self-renewal and differentiation. …
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Some human mesenchymal stem cells are more equal than others – origins and differences
It is a scientific success story that started approximately 40 years ago – and was initially met with skepticism. Although the pioneers of mesenchymal stem cell research were initially criticized, today thousands of publications and hundreds of clinical trials focus on multipotent cells. New MSC research is suggesting that in the end,…
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Stem cell therapy scientist: Finding inspiration outside his comfort zone
Crossing the border between medical and biomechanical research fuels the research of stem cell specialist Dr. Diego Correa. We talked to the Colombian-born stem cell scientist, a former clinician with training in mechanical engineering, about his studies with mesenchymal stem cells and their potential clinical applications in cell-based therapy. Soon Correa is going to publish what he believes will be his most important contribution to this field….
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Mesenchymal stem cells: why optimizing manufacturing processes is key for a successful application
Mesenchymal stem cells (MSCs) are the up-and-coming stars of cell therapy. They are able to differentiate, are very adaptable and can reduce inflammation, making them ideal for regenerative medicine approaches. But the demand for MSCs is far greater than supply. Pharmaceutical companies are racing to produce commercial-scale quantities of MSCs while guaranteeing quality standards….
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MSC reproducibility: Towards the standardization of Mesenchymal Stem Cells
For science to move forwards, the research we do must be reproducible. One of the ways we’re helping your work be as consistent as possible is through our characterized MSCs….
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From disease to healing: Exploring the roles of pericytes
They are multipotent, interact closely with endothelial cells, and are involved in immunosurveillance: the heterogeneous group of pericytes. These cells build the wall of blood vessels, and play a crucial role in the formation and maintenance of the vasculature. Due to their involvement in various pathophysiologies such as tumor angiogenesis, scientists are beginning to exploit their potential for therapeutic approaches….
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Why you should know your human mesenchymal stem cells inside out
Doctors, and patients with chronic diseases, are putting hope into new findings in regenerative medicine that are based on mesenchymal stem cell (MSC) research. As promising as some published results sound, they might be not reproducible – simply due to insufficient authentication and poor handling of cell cultures. Rigorous validation of cell identity is crucial for working with human mesenchymal stem cells – and,…
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Cancer stem cells in tumor biology
How do cancer stem cells develop? What is their role in tumor biology? What are current approaches to target cancer stem cells? And what are innovative solutions for working with them? Find all the answers in our blog post….
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A Home for Cancer Stem Cells: 3D Tumorspheres
Many scientists working in oncology focus on cancer stem cells (CSCs). Targeting these cells specifically could improve cancer therapy significantly. Because CSCs rely heavily on their environment, three-dimensional cultivation offers the unique opportunity to better understand this interaction. We talked to two scientists working in this field of cancer research.
In the human body,…
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PromoCell announces services for large-scale industrial lots of Mesenchymal Stem Cells
– New services for large-scale industrial lots allows customers to have high volumes of standardized MSC populations derived from bone marrow and adipose tissue
– Guaranteed MSC functionality and phenotype in accordance to ISCT* guidelines
– Optimized media with complete supplementation and expert technical support…
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Mesenchymal Stem Cells: Challenges and chances in cancer therapy
As the potential for using mesenchymal stem cells in cancer therapy grows, understanding the biology behind them can help inform and inspire innovative cancer therapies. Using high quality media and culture kits will increase the efficiency and usability of these highly demanded cells.
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