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Search results for: 'blog 3d skin model the promise for dermatology'

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  • 3D skin model: The promise for dermatology

    The development of 3D skin models has revolutionized in vitro studies in dermatology, offering a more representative platform for understanding skin structure and function in health and disease. In this article, we explain the biology of the human skin and explore the transformative potential of 3D skin models in reshaping our understanding of skin function…. Go To Page

  • Introducing a novel high throughput 3D wound healing model

    Non-healing wounds continue to cause significant patient burden. This blog details a novel 3D wound healing model that promises to facilitate the development of new treatments to promote wound healing.  … Go To Page

  • Mimicking the body’s largest organ in vitro with 3D skin models

    Researchers are increasingly using 3D cell cultures to study the skin’s features. Three-dimensional skin models offer the potential to study various diseases and test compounds in vitro. Dr. Florian Groeber-Becker from the Fraunhofer Institute for Silicate Research ISC in Wurzburg has developed a highly sophisticated skin model. It is the first thing people see when they look at us…. Go To Page

  • Using 3D Skin Models to Test Cosmetics

    Skin is the primary focus of cosmetic research. Since the European Union banned animal testing of cosmetics completely in 2013, three-dimensional skin models have been used to evaluate epidermal and dermal responses to cosmetic formulations. Such models provide a reliable tool to assess the functionality and safety of new cosmetic products…. Go To Page

  • PDX mouse: Pushing the possibilities with ex vivo cell culture

    Innovating mouse research such as PDX mouse models is key to improving cancer therapeutics. In translating scientific findings from mice to men, multiple techniques of collecting biological data are necessary. This article will explain how…. Go To Page

  • Keratinocytes

    Definition and Location Keratinocytes represent the major cell type of the epidermis, the outermost of the layers of the skin, making up about 90 percent of the cells there. They originate in the deepest layer of the epidermis, the stratum basale and move up to the final barrier layer of the skin,… Go To Page

  • Studying oxidative stress and skin aging using in vitro human cell culture models

    Oxidative stress results from an imbalance of pro- and anti-oxidants and leads to faster skin aging, inflammation and disease. Cell assays and primary cells provide the tools researchers need to study the oxidative process and its association with skin aging…. Go To Page

  • A young scientist seeks a method to knock out fibrosis

    Lab work is exciting, says Bastian Fischer. Even experiments that just yield their expected results inspire the young German scientist. Fischer is currently working on his PhD, and is investigating how fibrosis develops, so that effective therapies for this medical condition can be found. A scar is often all that remains of a deep cut – if anything remains at all…. Go To Page

  • Engineering a beating heart: The promise of cardiac spheroids

    Innovative cardiac models are key to understanding heart diseases and finding new, potentially life-saving therapies. Bioprinting cardiac spheroids using primary human cells is a significant step toward creating a human beating heart in vitro. This article will explain why…. Go To Page

  • Adipocytes: key players in metabolic homeostasis

    Adipocytes do more than simply store fat. They also play a role in metabolic diseases. Through better understanding of how adipose cells function and interact, researchers can develop new, targeted therapies for treating adipositas and diabetes. Our bodies and the bodies of all living organisms work like batteries: we get energy from food,… Go To Page

  • Cosmetics & Dermatology

    Since the total ban of animal experiments by strict EU regulations, scientists in the cosmetic industry have been relying on cultured primary cells in 2-D or 3-D. Our comprehensive portfolio for dermatological portfolio not only offers scientists to work comfortably with 2-D or 3-D cell cultures but also allows to generate organoids or perform co-culture experiments with different cell types from matched donors…. Go To Page

  • Invisible attraction: Using magnets to develop drugs in cell cultures

    Modern medicines are high-tech products. Developing medicines increasingly includes high throughput screening by fully automated analysis robots. One exciting high throughput approach uses magnetic 3D cell culture – which provides a more realistic model of human tissue than with 2D cell culture. The later a candidate drops out, the more expensive it is…. Go To Page

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