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Search results for: 'cells in action mimicking the bodys largest organ in vitro with 3d skin models'

Items 1-12 of 146 Results

  • Mimicking the body’s largest organ in vitro with 3D skin models

    Researchers are increasingly using 3D cell cultures to study the skin’s features. Three-dimensional skin models offer the potential to study various diseases and test compounds in vitro. Dr. Florian Groeber-Becker from the Fraunhofer Institute for Silicate Research ISC in Wurzburg has developed a highly sophisticated skin model. It is the first thing people see when they look at us…. Go To Page

  • 3D skin model: The promise for dermatology

    The development of 3D skin models has revolutionized in vitro studies in dermatology, offering a more representative platform for understanding skin structure and function in health and disease. In this article, we explain the biology of the human skin and explore the transformative potential of 3D skin models in reshaping our understanding of skin function…. Go To Page

  • Studying oxidative stress and skin aging using in vitro human cell culture models

    Oxidative stress results from an imbalance of pro- and anti-oxidants and leads to faster skin aging, inflammation and disease. Cell assays and primary cells provide the tools researchers need to study the oxidative process and its association with skin aging…. Go To Page

  • Introducing a novel high throughput 3D wound healing model

    Non-healing wounds continue to cause significant patient burden. This blog details a novel 3D wound healing model that promises to facilitate the development of new treatments to promote wound healing.  … Go To Page

  • Engineering a beating heart: The promise of cardiac spheroids

    Innovative cardiac models are key to understanding heart diseases and finding new, potentially life-saving therapies. Bioprinting cardiac spheroids using primary human cells is a significant step toward creating a human beating heart in vitro. This article will explain why…. Go To Page

  • Invisible attraction: Using magnets to develop drugs in cell cultures

    Modern medicines are high-tech products. Developing medicines increasingly includes high throughput screening by fully automated analysis robots. One exciting high throughput approach uses magnetic 3D cell culture – which provides a more realistic model of human tissue than with 2D cell culture. The later a candidate drops out, the more expensive it is…. Go To Page

  • Adipocytes: key players in metabolic homeostasis

    Adipocytes do more than simply store fat. They also play a role in metabolic diseases. Through better understanding of how adipose cells function and interact, researchers can develop new, targeted therapies for treating adipositas and diabetes. Our bodies and the bodies of all living organisms work like batteries: we get energy from food,… Go To Page

  • Super-resolution microscopy: Zooming in on the eorld of the influenza A virus

    It adapts quickly to the cellular defense mechanisms of the host and develops resistance against antiviral drugs: The influenza A virus is a major human pathogen with high variability. New super-resolution microscopy methods, as well as the use of human primary cells, currently allow better insights into the interactions between viruses and host cells…. Go To Page

  • Using 3D Skin Models to Test Cosmetics

    Skin is the primary focus of cosmetic research. Since the European Union banned animal testing of cosmetics completely in 2013, three-dimensional skin models have been used to evaluate epidermal and dermal responses to cosmetic formulations. Such models provide a reliable tool to assess the functionality and safety of new cosmetic products…. Go To Page

  • 3D cancer model

    De-skilling 3D tumor models Tissue-engineered 3D cancer models have grown in popularity with recent advances in cancer research. 3D models are more biomimetic than 2D cell monolayers cultured on tissue culture plastic. Examples are spheroids, tumorspheres, organoids, PDX and lately, tumoroids, which differ by origin (cell line or patient-derived), size, the complexity of cellular architecture and tumor environment…. Go To Page

  • Immuno-oncology

    A new in vitro strategy Immuno-oncology is a unique combination of oncology and immunology. By activating or amplifying the body’s natural defenses, immuno-oncology aims to boost the immune system to fight cancer better. Targeted antibodies or immunomodulators are well-known immunotherapies; adoptive cell therapy using CAR-T or TCR cells is particularly important,… Go To Page

  • 15 cell culture facts: Things about cell culture you might not know

    As a researcher working in cell culture, you must have a deep understanding of your specific research area. However, scientific knowledge is advancing rapidly. Therefore, keeping up with all the developments in cell-based research can be challenging. In this article, we present 15 facts about cell culture that can add to your knowledge…. Go To Page

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