Applications for our cancer media toolbox We have developed a toolbox of cancer cell media to establish primary cancer cell lines from biopsies, develop 3D tumor models or build screening assays. Below you find the different application areas to discover solutions for your workflow and choose the right medium or combination of media to leverage your cancer research. Overview 3D cancer model An easy way to establish a 3D cancer model from cell line or biopsy. Use the media toolbox to establish assay panels for drug discovery and to develop complex 3D models. Cancer stem cell selection Cancer stem cells (CSCs) are the tumor initiator and driver. Our toolbox conventiently selects CSCs and establishes healthy and defined patient-derived cancer cell lines. From biopsy to assay Are you working with patient-derived cancer cultures? Find out, how our toolbox helps you in setting up such cancer models and build advanced assays from your biopsy. Making best use of your PDX mouse The PDX mouse is the working model for cancer therapies. The toolbox helps leveraging your PDX mouse project for better decision making and translation into clinic. Extracellular vesicles in cancer You are investigating EVs in cancer biology or using them in diagnostics or drug delivery? Our toolbox gives you an edge. Check out our EV-depleted and GMP-compliant media. Immuno-oncology CAR-T and TCR cell therapies have seen the light of modern cancer treatment. Not only the T cell but also the proper cancer target cell, decide over the success in the clinic. Tumor microenvironment The TME has a significant impact on drug response in cancer therapies. With our toolbox you can set up a complex organoid model combining cancer and non-cancer cells. CSC therapy To effectively treat cancer, you need to target cancer stem cells (CSCs). Check out how our toolbox enables pure CSC isolation and expansion for advanced CSC therapy development. The toolbox consists of three media, which all support and maintain cancer stem cells in a cancer cell culture. The choice of the medium allows to control, which additional types of cancer and non-cancer cells are supported or vice versa, which cell types will not grow in the medium. Depending on the medium and cancer type, 2D or 3D cell cultures can be generated. How do the media work? Cancer stem cells share properties irrespectively of their origin such as self-renewal capability or anoikis resistance. Find more information, which properties we have chosen to design the unique features of our toolbox media.
