Red-fluorescent Tetramethylrhodamine-α-Bungarotoxin binds to the nicotinic acetylcholine receptor (AChR) with high affinity thereby inhibiting the binding of acetylcholine (ACh) to the receptor and blocking neuromuscular transmission. Thus, labeled alpha-bungarotoxin conjugates can be used to facilitate identification of nicotinic AChRs and image the distribution of the receptor at the neuromuscular junctions. See also our other dye- and biotin-labeled αbungarotoxins, e.g. green-fluorescent Fluorescein-alpha-Bungarotoxin (PK-CA707-00011).
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