CETP Activity Assay Kit

Simple, rapid & convenient fluorometric assay to measure CETP activity in animal serum, plasma or recombinant protein.

Please be aware that this product will be discontinued and will only be available until: 21.12.2021
CETP Activity Assay Kit
100 assays
$ 709.00

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CETP Activity Assay Kit

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Cholesteryl ester transfer protein (CETP) is a plasma protein that transfers a cholesteryl ester from HDL to LDL or VLDL in exchange for a triglyceride. HDL plays an important role in lipid metabolism and cardiovascular health. HDL transports cholesterol to the liver for excretion or to steroidogenic tissues for steroid synthesis. HDL also plays an important role in the reverse cholesterol transport pathway, removing cholesterol from lipidfilled macrophages, protecting against atherosclerosis. Because of this function, CETP is viewed as a target to increase HDL, with CETP inhibition an active area of research and several CETP inhibitors atvarious stages of drug development.

PromoCell’s CETP Activity Assay Kit uses a self-quenched fluorescent neutral lipid that can be measured when transferred to an acceptor molecule. The fluorometric intensity is directly proportional to the amount of neutral lipid transfer. Rabbit serum is provided as a positive control and the CETP inhibitor Torcetrapib is also included for assay validation. This assay kit, in addition to measuring activity in serum, is also suitable for testing activity of recombinant protein.

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