AG-120 (Ivosidenib)

A potent isocitrate dehydrogenase type 1 (IDH1) inhibitor.

Please be aware that this product will be discontinued and will only be available until: 21.12.2021

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AG-120 (Ivosidenib) 5 mg

AG-120 (Ivosidenib) 25 mg

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AG-120 is a potent isocitrate dehydrogenase type 1 (IDH1) inhibitor, with potential antineoplastic activity. Upon oral administration it specifically inhibits a mutated form of IDH1 in the cytoplasm inhibiting the formation of oncometabolite, 2-hydroxyglutarate (2HG). This leads to induction of cellular differentiation and an inhibition of cellular proliferation.