Adiponectin, also referred to as Acrp30, AdipoQ and GBP-28, is a recently discovered 244 amino acid protein, the product of the apM1 gene, which is physiologically active and specifically and highly expressed in adipose cells (adipokine). The protein belongs to the soluble defence collagen superfamily; it has a collagen-like domain structurally homologous with collagen VIII and X and complement factor C1q-like globular domain. Adiponectin forms homotrimers, which are the building blocks for higher order complexes found circulating in serum. The human Adiponectin is expressed in E. coli as a recombinant 25.1 kDa sinle, non-glycosylated polypeptide chain containing 231 amino acid residues.
|Molecular Mass||26.40 kDa|
|Specific Activity||see below|
|Formulation||Liquid; 1 mg/ml in PBS (pH 7.40) containing 1 mM DTT.|
|Purity||Greater than 90% (determined by SDS-PAGE analysis).|
|Endotoxin Level||< 0.10 ng per µg rHu Acrp30 (1EU/µg).|
|Stability & Storage||The protein solution , though stable at 4°C for up to one week, is best stored at -20°C. Avoid repeated freeze-thaw cycles.|