4-Hydroxynonenal

An inhibitor of Sirtuin 3 (SIRT3) and marker of lipid peroxidation.

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4-Hydroxynonenal 1 mg

4-Hydroxynonenal 5 mg

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4-hydroxynonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid. 4-HNE is widely used as a marker of lipid peroxidation. It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. It also inhibits Sirtuin-3 (SIRT3) via thiol-specific modification.