α-Cyano-4-hydroxycinnamic acid

A a monocarboxylate transporter (MCT) inhibitor that displays antitumor and antiangiogenic activity in gliomas in vivo, and also decreases glycolytic metabolism, migration, and invasion in U251 cells.

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α-Cyano-4-hydroxycinnamic acid 500 mg

α-Cyano-4-hydroxycinnamic acid 1 g

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α-Cyano-4-hydroxycinnamate (4-CIN) is a monocarboxylate transporter (MCT) inhibitor. Displays antitumor and antiangiogenic activity in gliomas in vivo; decreases glycolytic metabolism, migration, and invasion in U251 cells. Also blocks lactate efflux from glioma cells and sensitizes cells to irradiation.