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3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-p yrazole-1-carbothioamide; Stem Cell Fate Regulator & Protein Tyrosine Kinase Inhibitor
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A potent and selective G9a/GLP histone lysine methyltransferase inhibitor that has been shown to inhibit H3K9 methylation in prostate cancer PC3 cells.
A potent and selective p300/CREB-binding protein (CBP) HAT domain inhibitor that reduces proliferation of diverse cancer cells.
An aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor which disrupts spheroid formation and cell viability.
A broad-spectrum inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity.
A potent steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase (CYP17) inhibitor.
A fluorogenic ACE-2 (Angiotensin I-converting enzyme 2) substrate.
A potent ACE2 (Angiotensin-Converting Enzyme 2) inhibitor.
A water-soluble derivative of the potent and selective adiponectin receptor agonist AdipoRon that is also an activator of PPARα and AMPK signaling pathways.
AFC can be used as a fluorescent marker and standard in fluororometric caspase assays
A potent isocitrate dehydrogenase type 1 (IDH1) inhibitor.
A potent IDH2 (Isocitrate dehydrogenase 2) inhibitor.
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