An inhibitor of Sirtuin 3 (SIRT3) and marker of lipid peroxidation.
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An epigenetic modifier and inhibitor of DNA methyltransferase, causing hypomethylation of DNA and cellular differentiation or apoptosis. It is believed to exert its antineoplastic effects.
An inhibitor of histone deacetylase (HDAC) that also causes reactive oxygen species, DNA damage and apoptosis in MCF-7 breast cancer cells.
An inhibitor of glucose-6-phosphate dehydrogenase (G6PD) that also exhibits anticancer activity in vitro, causes oxidative stress, and sensitizes cells to anticancer agents and radiation.
Displays anti-oxidant, anti-inflammatory and anti-tumor properties and has been shown to inhibit COX-2 expression.
An immunosuppressive and antileukemic agent. It has been found to inhibit MERS-CoV PL Protease.
A non-selective, reversible and competitive inhibitor of NOS isoforms in vitro.
A potent and selective G9a/GLP histone lysine methyltransferase inhibitor that has been shown to inhibit H3K9 methylation in prostate cancer PC3 cells.
A potent and selective p300/CREB-binding protein (CBP) HAT domain inhibitor that reduces proliferation of diverse cancer cells.
An aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor which disrupts spheroid formation and cell viability.
A broad-spectrum inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity.
A potent steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase (CYP17) inhibitor.
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